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EMC1 - ER membrane protein complex subunit 1

Contributes to membrane insertase activity. Involved in tail-anchored membrane protein insertion into ER membrane. Located in endomembrane system. Is expressed in adult head; adult midgut enterocyte; enteroblast; and enteroendocrine cell. Used to study cerebellar atrophy, visual impairment, and psychomotor retardation and intestinal cancer. Human ortholog(s) of this gene implicated in cerebellar atrophy, visual impairment, and psychomotor retardation. Orthologous to human EMC1 (ER membrane protein complex subunit 1). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa