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tex tex [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40983, updated on 4-Jan-2025

Summary

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Official Symbol
texprovided by FlyBase
Official Full Name
texprovided by FlyBase
Primary source
FLYBASE:FBgn0037569
Locus tag
Dmel_CG9615
See related
AllianceGenome:FB:FBgn0037569
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG9615; Dmel\CG9615; TEX1; Thoc3
Summary
Predicted to be involved in mRNA export from nucleus. Predicted to be part of THO complex part of transcription export complex. Is expressed in several structures, including amnioserosa; dorsal ectoderm; hindgut anlage; inclusive hindgut primordium; and trunk mesoderm. Orthologous to human THOC3 (THO complex subunit 3). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See tex in Genome Data Viewer
Location:
84F10-84F11; 3-48 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8307473..8308645, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4133195..4134367, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L1 Neighboring gene neuronally altered carbohydrate Neighboring gene suppressor-of-G2-allele-of-skp1 Neighboring gene mir-4918 stem loop Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Splicing-independent loading of TREX on nascent RNA is required for efficient expression of dual-strand piRNA clusters in Drosophila. Hur JK, et al. Genes Dev, 2016 Apr 1. PMID 27036967, Free PMC Article
  2. mRNA export and the TREX complex. Katahira J. Biochim Biophys Acta, 2012 Jun. PMID 22178508
  3. A length-dependent evolutionarily conserved pathway controls nuclear export of circular RNAs. Huang C, et al. Genes Dev, 2018 May 1. PMID 29773557, Free PMC Article
  4. Computational and experimental identification of mirtrons in Drosophila melanogaster and Caenorhabditis elegans. Chung WJ, et al. Genome Res, 2011 Feb. PMID 21177960, Free PMC Article
  5. Genome-wide analysis of mRNAs regulated by the THO complex in Drosophila melanogaster. Rehwinkel J, et al. Nat Struct Mol Biol, 2004 Jun. PMID 15133499

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in mRNA export from nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mRNA export from nucleus IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of THO complex part of transcription export complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of transcription export complex ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
tex
Names
CG9615-PA
tex-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    8307473..8308645 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141527.3 → NP_649784.1  tex [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649784.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MSF3, Q9VHT2
    Related
    FBpp0081350
    Conserved Domains (2) summary
    sd00039
    Location:32 → 70
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:19 → 263
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MSF3 Q8MSF3
Q9VHT2 Q9VHT2

Gene LinkOut

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