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Coq2 - Coenzyme Q biosynthesis protein 2

Predicted to enable 4-hydroxybenzoate polyprenyltransferase activity. Involved in defense response to other organism and determination of adult lifespan. Predicted to be located in membrane. Predicted to be active in mitochondrial inner membrane. Is expressed in adult head; embryonic/larval midgut; indirect flight muscle cell; and organism. Used to study nephrotic syndrome and primary coenzyme Q10 deficiency 1. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 1. Orthologous to human COQ2 (coenzyme Q2, polyprenyltransferase). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa