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Or85a Odorant receptor 85a [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40991, updated on 9-Dec-2024

Summary

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Official Symbol
Or85aprovided by FlyBase
Official Full Name
Odorant receptor 85aprovided by FlyBase
Primary source
FLYBASE:FBgn0037576
Locus tag
Dmel_CG7454
See related
AllianceGenome:FB:FBgn0037576
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
85a; 85A.4; CG7454; Dmel\CG7454; DmOr85a; DmOR85A; DOR31; Or-85a; or85a; OR85a
Summary
Enables ionotropic olfactory receptor activity. Involved in detection of chemical stimulus involved in sensory perception of smell. Located in plasma membrane. Is expressed in adult olfactory receptor neuron Or85a; antennal basiconic sensillum ab2; and antennal lobe glomerulus DM5. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Or85a in Genome Data Viewer
Location:
84F11-84F11; 3-48 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8321747..8323054)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4147469..4148776)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45215 Neighboring gene Coenzyme Q biosynthesis protein 2 Neighboring gene Copper transporter 1B Neighboring gene Pox meso Neighboring gene uncharacterized protein Neighboring gene Cytochrome c oxidase subunit 7A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Measuring activity in olfactory receptor neurons in Drosophila: Focus on spike amplitude. Martin F, et al. J Insect Physiol, 2016 Dec. PMID 27614176
  2. The Evolution of Olfactory Gene Families in Drosophila and the Genomic Basis of chemical-Ecological Adaptation in Drosophila suzukii. Ramasamy S, et al. Genome Biol Evol, 2016 Aug 16. PMID 27435796, Free PMC Article
  3. Odorant reception in the malaria mosquito Anopheles gambiae. Carey AF, et al. Nature, 2010 Mar 4. PMID 20130575, Free PMC Article
  4. Subunit contributions to insect olfactory receptor function: channel block and odorant recognition. Nichols AS, et al. Chem Senses, 2011 Nov. PMID 21677030, Free PMC Article
  5. Sensory processing during sleep in Drosophila melanogaster. French AS, et al. Nature, 2021 Oct. PMID 34588694

See all (80) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ionotropic olfactory receptor activity HDA PubMed 
enables odorant binding IEA
Inferred from Electronic Annotation
more info
  
enables odorant binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in detection of chemical stimulus involved in sensory perception of smell HDA PubMed 
involved_in detection of chemical stimulus involved in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in dendrite membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane HDA PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
odorant receptor 85a
Names
CG7454-PA
Or85a-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    8321747..8323054
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079553.1 → NP_524277.1  odorant receptor 85a [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524277.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VHS4
    UniProtKB/TrEMBL
    D7F910, D7F911, D7F913
    Related
    FBpp0081326, FBtr0081836
    Conserved Domains (1) summary
    pfam02949
    Location:77 → 379
    7tm_6; 7tm Odorant receptor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VHS4.1 Q9VHS4

Gene LinkOut

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