Ras85D - Ras oncogene at 85D
Enables G protein activity and protein serine/threonine kinase activator activity. Involved in several processes, including cell surface receptor protein tyrosine kinase signaling pathway; instar larval or pupal development; and respiratory system development. Located in plasma membrane. Is expressed in several structures, including adult head; adult heart; brain; germline cell; and imaginal disc. Used to study Noonan syndrome 3; cancer (multiple); and heart disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including Noonan syndrome (multiple); carcinoma (multiple); cardiofaciocutaneous syndrome (multiple); hematologic cancer (multiple); and high grade glioma (multiple). Orthologous to several human genes including HRAS (HRas proto-oncogene, GTPase). [provided by Alliance of Genome Resources, Nov 2024]
NCBI Orthologs
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