Scm - Sex comb on midleg
Enables PRC1 complex binding activity; identical protein binding activity; and sequence-specific DNA binding activity. Involved in several processes, including axonogenesis; follicle cell of egg chamber development; and regulation of gene expression. Located in nucleus and polytene chromosome. Is expressed in several structures, including adult head; ganglia; ovary; and presumptive embryonic/larval central nervous system. Orthologous to human SCMH1 (Scm polycomb group protein homolog 1) and SCML2 (Scm polycomb group protein like 2). [provided by Alliance of Genome Resources, Dec 2024]
NCBI Orthologs
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Protein alignment
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