jumu - jumeau
Enables transcription cis-regulatory region binding activity. Involved in several processes, including defense response to fungus; nucleolus organization; and positive regulation of receptor signaling pathway via JAK-STAT. Located in euchromatin; nucleolus; and polytene chromosome chromocenter. Is expressed in several structures, including RP neuron; cardiogenic mesoderm; ganglia; gonad; and somatic precursor cell. Human ortholog(s) of this gene implicated in T-cell immunodeficiency, congenital alopecia, and nail dystrophy; alopecia; nail disease; and primary immunodeficiency disease. Orthologous to human FOXN1 (forkhead box N1) and FOXN4 (forkhead box N4). [provided by Alliance of Genome Resources, Dec 2024]
NCBI Orthologs
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Protein alignment
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Species | Gene | Architecture | aa |
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