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Ugt35B1 UDP-glycosyltransferase family 35 member B1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41333, updated on 4-Jan-2025

Summary

Official Symbol
Ugt35B1provided by FlyBase
Official Full Name
UDP-glycosyltransferase family 35 member B1provided by FlyBase
Primary source
FLYBASE:FBgn0026314
Locus tag
Dmel_CG6649
See related
AllianceGenome:FB:FBgn0026314
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
AC 006491B; CG6649; Dmel\CG6649; DmeUgt35b; UDPGT2; Ugt-35b; ugt35b; Ugt35b; Ugt35B; UGT35b; UGT35B1; Ugt86Db
Summary
Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in adult head; leg; and third segment of antenna. Human ortholog(s) of this gene implicated in several diseases, including alcoholic pancreatitis; bilirubin metabolic disorder (multiple); cholecystolithiasis; cholelithiasis; and female reproductive organ cancer (multiple). Orthologous to several human genes including UGT1A1 (UDP glucuronosyltransferase family 1 member A1); UGT1A10 (UDP glucuronosyltransferase family 1 member A10); and UGT1A3 (UDP glucuronosyltransferase family 1 member A3). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See Ugt35B1 in Genome Data Viewer
Location:
86D5-86D5; 3-50 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11168503..11170246, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (6994225..6995968, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene UDP-glycosyltransferase family 35 member E1 Neighboring gene UDP-glycosyltransferase family 35 member E2 Neighboring gene UDP-glycosyltransferase family 35 member A1 Neighboring gene UDP-glycosyltransferase family 304 member A1

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables UDP-glycosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables UDP-glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables UDP-glycosyltransferase activity ISM
Inferred from Sequence Model
more info
PubMed 
enables UDP-glycosyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in glycosylation ISM
Inferred from Sequence Model
more info
PubMed 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane ISM
Inferred from Sequence Model
more info
PubMed 
located_in membrane ISM
Inferred from Sequence Model
more info
PubMed 

General protein information

Preferred Names
UDP-glycosyltransferase family 35 member B1
Names
CG6649-PA
UDP-glycosyltransferase
UDP-glycosyltransferase 35b
Ugt35B1-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    11168503..11170246 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_079589.3NP_524313.2  UDP-glycosyltransferase family 35 member B1 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524313.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VGT0, Q9XYN3
    Related
    FBpp0081851
    Conserved Domains (2) summary
    PHA03392
    Location:8466
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    TIGR01426
    Location:26438
    MGT; glycosyltransferase, MGT family