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ZnT86D Zinc transporter 86D [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41342, updated on 4-Jan-2025

Summary

Official Symbol
ZnT86Dprovided by FlyBase
Official Full Name
Zinc transporter 86Dprovided by FlyBase
Primary source
FLYBASE:FBgn0037875
Locus tag
Dmel_CG6672
See related
AllianceGenome:FB:FBgn0037875
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
cg6672; CG6672; Dmel\CG6672; dZnT7; dZNT7; dZnT86D; dZNT86D; ZNT86D
Summary
Predicted to enable zinc ion transmembrane transporter activity. Involved in detoxification of zinc ion. Located in Golgi apparatus and basolateral plasma membrane. Is expressed in adult head. Used to study carcinoma. Orthologous to human SLC30A7 (solute carrier family 30 member 7). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See ZnT86D in Genome Data Viewer
Location:
86D8-86D8; 3-50 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11212308..11214539, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7038030..7040261, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Succinate dehydrogenase, subunit C Neighboring gene Translationally controlled tumor protein Neighboring gene Ribosomal protein S25 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables zinc ion transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables zinc ion transmembrane transporter activity IC
Inferred by Curator
more info
PubMed 
enables zinc ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in detoxification of zinc ion IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in intracellular zinc ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intracellular zinc ion homeostasis IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in zinc ion import into Golgi lumen IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in zinc ion transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
PubMed 
located_in basolateral plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytoplasmic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc transporter 86D
Names
CG6672-PA
ZnT86D-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    11212308..11214539 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141792.3NP_650049.1  zinc transporter 86D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650049.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VGS1
    Related
    FBpp0081847
    Conserved Domains (2) summary
    TIGR01297
    Location:46366
    CDF; cation diffusion facilitator family transporter
    pfam01545
    Location:46286
    Cation_efflux; Cation efflux family