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KP78a KP78a [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41362, updated on 9-Dec-2024

Summary

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Official Symbol
KP78aprovided by FlyBase
Official Full Name
KP78aprovided by FlyBase
Primary source
FLYBASE:FBgn0026064
Locus tag
Dmel_CG6715
See related
AllianceGenome:FB:FBgn0026064
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG6715; Dmel\CG6715; Kp78A; KP78A
Summary
Predicted to enable protein serine/threonine kinase activity and tau-protein kinase activity. Predicted to be involved in intracellular signal transduction and microtubule cytoskeleton organization. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See KP78a in Genome Data Viewer
Location:
86E2-86E2; 3-51 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11346294..11353131, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7172016..7178853, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45055 Neighboring gene long non-coding RNA:CR46008 Neighboring gene prospero Neighboring gene long non-coding RNA:CR46009 Neighboring gene long non-coding RNA:CR46010 Neighboring gene KP78b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. LKB1 regulates polarity remodeling and adherens junction formation in the Drosophila eye. Amin N, et al. Proc Natl Acad Sci U S A, 2009 Jun 2. PMID 19443685, Free PMC Article
  2. The Drosophila homolog of C. elegans PAR-1 organizes the oocyte cytoskeleton and directs oskar mRNA localization to the posterior pole. Shulman JM, et al. Cell, 2000 May 12. PMID 10830165
  3. Drosophila LKB1 is required for the assembly of the polarized actin structure that allows spermatid individualization. Couderc JL, et al. PLoS One, 2017. PMID 28767695, Free PMC Article
  4. Reverse transcriptional profiling: non-correspondence of transcript level variation and proximal promoter polymorphism. Brown RP, et al. BMC Genomics, 2005 Aug 17. PMID 16107220, Free PMC Article
  5. Genes involved in Drosophila glutamate receptor expression and localization. Liebl FL, et al. BMC Neurosci, 2005 Jun 28. PMID 15985179, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables tau-protein kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
KP78a
Names
CG6715-PB
KP78a-PB
NP_650066.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    11346294..11353131 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141809.3 → NP_650066.1  KP78a [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650066.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O17048, Q9VGP9
    Related
    FBpp0290641
    Conserved Domains (2) summary
    smart00220
    Location:98 → 349
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:98 → 349
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O17048 O17048
Q3YNC4 Q3YNC4
Q9VGP9 Q9VGP9

Gene LinkOut

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