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CG17230 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41376, updated on 9-Dec-2024

Summary

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Official Symbol
CG17230provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0046225
Locus tag
Dmel_CG17230
See related
AllianceGenome:FB:FBgn0046225
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:GH24095; CG5286; Dmel\CG17230
Summary
Predicted to be involved in apoptotic process. Predicted to be active in keratin filament. Is expressed in chordotonal neurons; organism; and spermatogonium. Orthologous to human TCHP (trichoplein keratin filament binding). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG17230 in Genome Data Viewer
Location:
86E5-86E7; 3-51 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11437785..11467372)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7263507..7293094)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Exonuclease 3'-5' domain-containing 2 Neighboring gene uncharacterized protein Neighboring gene sarcomere length short Neighboring gene mir-4945 stem loop Neighboring gene Peptidoglycan recognition protein LB Neighboring gene long non-coding RNA:CR45581 Neighboring gene defective proboscis extension response 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Tissue-specific down-regulation of S-adenosyl-homocysteine via suppression of dAhcyL1/dAhcyL2 extends health span and life span in Drosophila. Parkhitko AA, et al. Genes Dev, 2016 Jun 15. PMID 27313316, Free PMC Article
  2. Survey of the Ciliary Motility Machinery of Drosophila Sperm and Ciliated Mechanosensory Neurons Reveals Unexpected Cell-Type Specific Variations: A Model for Motile Ciliopathies. Zur Lage P, et al. Front Genet, 2019. PMID 30774648, Free PMC Article
  3. Genome-wide prediction of Polycomb/Trithorax response elements in Drosophila melanogaster. Ringrose L, et al. Dev Cell, 2003 Nov. PMID 14602076
  4. Somatic, germline and sex hierarchy regulated gene expression during Drosophila metamorphosis. Lebo MS, et al. BMC Genomics, 2009 Feb 13. PMID 19216785, Free PMC Article
  5. In vivo analysis of proteomes and interactomes using Parallel Affinity Capture (iPAC) coupled to mass spectrometry. Rees JS, et al. Mol Cell Proteomics, 2011 Jun. PMID 21447707, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in apoptotic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in keratin filament IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG17230-PA
CG17230-PB
CG17230-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    11437785..11467372
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141820.2 → NP_650077.1  uncharacterized protein Dmel_CG17230, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650077.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K4X4
    Related
    FBpp0081868
    Conserved Domains (1) summary
    COG1196
    Location:49 → 350
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  2. NM_001300360.1 → NP_001287289.1  uncharacterized protein Dmel_CG17230, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287289.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K4X4
    Conserved Domains (1) summary
    COG1196
    Location:49 → 350
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  3. NM_169394.2 → NP_731578.1  uncharacterized protein Dmel_CG17230, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_731578.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K4X4
    Related
    FBpp0081869
    Conserved Domains (1) summary
    COG1196
    Location:49 → 350
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7K4X4 Q7K4X4

Gene LinkOut

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