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DCAF12 - DDB1 and CUL4 associated factor 12

Enables ubiquitin-like ligase-substrate adaptor activity. Involved in several processes, including autophagic cell death; evoked neurotransmitter secretion; and positive regulation of hippo signaling. Part of Cul4-RING E3 ubiquitin ligase complex. Is active in cytoplasm; nucleus; and presynapse. Is expressed in organism. Orthologous to human DCAF12 (DDB1 and CUL4 associated factor 12); DCAF12L1 (DDB1 and CUL4 associated factor 12 like 1); and DCAF12L2 (DDB1 and CUL4 associated factor 12 like 2). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa