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ATP8B - ATPase 8B

Predicted to enable ATPase-coupled intramembrane lipid transporter activity. Involved in detection of chemical stimulus involved in sensory perception of smell and regulation of protein localization. Located in cilium and sensory dendrite. Is expressed in adult antennal sensillum; adult olfactory receptor neurons; and organism subdivision. Human ortholog(s) of this gene implicated in benign recurrent intrahepatic cholestasis 1; intrahepatic cholestasis; intrahepatic cholestasis of pregnancy 1; and progressive familial intrahepatic cholestasis 1. Orthologous to several human genes including ATP8B2 (ATPase phospholipid transporting 8B2) and ATP8B4 (ATPase phospholipid transporting 8B4 (putative)). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to ATP8B

NCBI Orthologs

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Species Gene Architecture aa