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psmd8 proteasome 26S subunit, non-ATPase 8 [ Danio rerio (zebrafish) ]

Gene ID: 415221, updated on 4-Jan-2025

Summary

Official Symbol
psmd8provided by ZNC
Official Full Name
proteasome 26S subunit, non-ATPase 8provided by ZNC
Primary source
ZFIN:ZDB-GENE-040625-136
See related
Ensembl:ENSDARG00000020454 AllianceGenome:ZFIN:ZDB-GENE-040625-136
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fa93g07; fb17c09; fb49a10; zgc:86762; wu:fa93g07; wu:fb17c09; wu:fb49a10
Summary
Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within proteolysis. Predicted to be part of proteasome regulatory particle, lid subcomplex. Predicted to be active in nucleus. Orthologous to human PSMD8 (proteasome 26S subunit, non-ATPase 8). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See psmd8 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (44615595..44623646, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (44622142..44630192, complement)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene DEAH (Asp-Glu-Ala-His) box polypeptide 34 Neighboring gene sprouty related EVH1 domain containing 3 Neighboring gene BRD4 interacting chromatin remodeling complex associated protein Neighboring gene EH-domain containing 2b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of proteasome complex IEA
Inferred from Electronic Annotation
more info
 
part_of proteasome regulatory particle IEA
Inferred from Electronic Annotation
more info
 
part_of proteasome regulatory particle, lid subcomplex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
26S proteasome non-ATPase regulatory subunit 8
Names
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002131.2NP_001002131.1  26S proteasome non-ATPase regulatory subunit 8

    See identical proteins and their annotated locations for NP_001002131.1

    Status: VALIDATED

    Source sequence(s)
    BX908775, BX936429
    UniProtKB/TrEMBL
    A0A8M1MZZ9, Q6IQH4
    Related
    ENSDARP00000025160.8, ENSDART00000005431.9
    Conserved Domains (1) summary
    pfam10075
    Location:118232
    CSN8_PSD8_EIF3K; CSN8/PSMD8/EIF3K family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    44615595..44623646 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)