ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 [Gallus gallus (chicken)] - Gene

Summary

Symbol: ARIH1provided by CGNC
Full Name: ariadne RBR E3 ubiquitin protein ligase 1provided by CGNC
Primary source: CGNC:1344
See related: Ensembl:ENSGALG00010021577
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	10	NC_052541.1 (1664334..1713625)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	10	NC_052582.1 (1538180..1587445)

Chromosome 10 - NC_052541.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

T10BE342 (e-PCR)
- UniSTS:470605

T10BE340 (e-PCR)
- UniSTS:470425

T10BE397 (e-PCR)
- UniSTS:470479

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ubiquitin conjugating enzyme binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ubiquitin protein ligase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein polyubiquitination	IEA Inferred from Electronic Annotation more info	PubMed
involved_in ubiquitin-dependent protein catabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed
part_of ubiquitin ligase complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: E3 ubiquitin-protein ligase ARIH1

Names: ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1; ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1

NP_001025558.2

EC 2.3.2.27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001030387.3 → NP_001025558.2 E3 ubiquitin-protein ligase ARIH1

Status: VALIDATED

Source sequence(s)

JAENSK010000245

UniProtKB/TrEMBL

A0A1D5PH50, A0A8V0ZDD5

Related

ENSGALP00010031299.1, ENSGALT00010052375.1

Conserved Domains (3) summary

smart00647
Location:252 → 312

IBR; In Between Ring fingers

cd16626
Location:180 → 237

RING-HC_RBR_HHARI; RING finger, HC subclass, found in human homolog of Drosophila ariadne (HHARI) and similar proteins

pfam01485
Location:334 → 374

IBR; IBR domain, a half RING-finger domain