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Polr3C RNA polymerase III subunit C [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41542, updated on 9-Dec-2024

Summary

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Official Symbol
Polr3Cprovided by FlyBase
Official Full Name
RNA polymerase III subunit Cprovided by FlyBase
Primary source
FLYBASE:FBgn0038057
Locus tag
Dmel_CG12267
See related
AllianceGenome:FB:FBgn0038057
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG12267; Dmel\CG12267; dPolr3c; RPC82
Summary
Predicted to enable single-stranded DNA binding activity. Predicted to be involved in DNA-templated transcription. Predicted to be part of RNA polymerase III complex. Is expressed in organism. Orthologous to human POLR3C (RNA polymerase III subunit C). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Polr3C in Genome Data Viewer
Location:
87B11-87B11; 3-52 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12460414..12462418)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8286136..8288140)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene toys are us Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Heat shock protein 70 Ba

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Increased expression of fragmented tRNA promoted neuronal necrosis. Cao Y, et al. Cell Death Dis, 2021 Aug 30. PMID 34462418, Free PMC Article
  2. Drosophila TIF-IA is required for ribosome synthesis and cell growth and is regulated by the TOR pathway. Grewal SS, et al. J Cell Biol, 2007 Dec 17. PMID 18086911, Free PMC Article
  3. Drosophila growth and development in the absence of dMyc and dMnt. Pierce SB, et al. Dev Biol, 2008 Mar 15. PMID 18241851, Free PMC Article
  4. In silico identification of Drosophila melanogaster genes encoding RNA polymerase subunits. Marygold SJ, et al. MicroPubl Biol, 2020 Oct 20. PMID 33274328, Free PMC Article
  5. New levels of transcriptome complexity at upper thermal limits in wild Drosophila revealed by exon expression analysis. Telonis-Scott M, et al. Genetics, 2013 Nov. PMID 24002645, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of RNA polymerase III complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of RNA polymerase III complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
RNA polymerase III subunit C
Names
CG12267-PA
CG12267-PB
Polr3C-PA
Polr3C-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    12460414..12462418
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001202283.1 → NP_001189212.1  RNA polymerase III subunit C, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001189212.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q961B1, Q9VG60
    Conserved Domains (2) summary
    pfam05645
    Location:143 → 324
    RNA_pol_Rpc82; RNA polymerase III subunit RPC82
    pfam08221
    Location:7 → 65
    HTH_9; RNA polymerase III subunit RPC82 helix-turn-helix domain

  2. NM_141950.3 → NP_650207.1  RNA polymerase III subunit C, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650207.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q961B1, Q9VG60
    Related
    FBpp0082104
    Conserved Domains (2) summary
    pfam05645
    Location:143 → 324
    RNA_pol_Rpc82; RNA polymerase III subunit RPC82
    pfam08221
    Location:7 → 65
    HTH_9; RNA polymerase III subunit RPC82 helix-turn-helix domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VG60 Q9VG60

Gene LinkOut

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