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NijC Ninjurin C [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41568, updated on 4-Jan-2025

Summary

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Official Symbol
NijCprovided by FlyBase
Official Full Name
Ninjurin Cprovided by FlyBase
Primary source
FLYBASE:FBgn0038079
Locus tag
Dmel_CG14394
See related
AllianceGenome:FB:FBgn0038079
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG14394; Dmel\CG14394
Summary
Predicted to be involved in cell adhesion. Predicted to be located in membrane. Is expressed in wing disc. Orthologous to several human genes including NINJ2 (ninjurin 2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See NijC in Genome Data Viewer
Location:
87C5-87C6; 3-52 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12695129..12697379)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8520851..8523101)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Actin-related protein 1 Neighboring gene uncharacterized protein Neighboring gene Putative Achaete Scute Target 1 Neighboring gene uncharacterized protein Neighboring gene DNA polymerase theta Neighboring gene Malic enzyme

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila Past1 is involved in endocytosis and is required for germline development and survival of the adult fly. Olswang-Kutz Y, et al. J Cell Sci, 2009 Feb 15. PMID 19174465
  2. An MMP liberates the Ninjurin A ectodomain to signal a loss of cell adhesion. Zhang S, et al. Genes Dev, 2006 Jul 15. PMID 16815999, Free PMC Article
  3. Combining mapping and arraying: An approach to candidate gene identification. Wayne ML, et al. Proc Natl Acad Sci U S A, 2002 Nov 12. PMID 12415114, Free PMC Article
  4. Synergistic activation by Glass and Pointed promotes neuronal identity in the Drosophila eye disc. Wang H, et al. Nat Commun, 2024 Aug 17. PMID 39154080, Free PMC Article
  5. The Spalt Transcription Factors Generate the Transcriptional Landscape of the Drosophila melanogaster Wing Pouch Central Region. Organista MF, et al. PLoS Genet, 2015 Aug. PMID 26241320, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
  
involved_in tissue regeneration IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ninjurin C
Names
CG14394-PB
CG14394-PC
CG14394-PD
CG14394-PE
CG14394-PF
CG14394-PG
NijC-PB
NijC-PC
NijC-PD
NijC-PE
NijC-PF
NijC-PG

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    12695129..12697379
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001104290.2 → NP_001097760.1  ninjurin C, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097760.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4V5X1
    Conserved Domains (1) summary
    pfam04923
    Location:19 → 119
    Ninjurin

  2. NM_001104291.2 → NP_001097761.1  ninjurin C, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097761.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A8JQY8
    Conserved Domains (1) summary
    pfam04923
    Location:19 → 122
    Ninjurin

  3. NM_001104292.2 → NP_001097762.1  ninjurin C, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097762.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A8JQY7
    Conserved Domains (1) summary
    pfam04923
    Location:19 → 119
    Ninjurin

  4. NM_001144571.2 → NP_001138043.1  ninjurin C, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001138043.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7Z0S7
    Conserved Domains (1) summary
    pfam04923
    Location:14 → 114
    Ninjurin

  5. NM_001144569.2 → NP_001138041.1  ninjurin C, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001138041.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7Z0S8
    Conserved Domains (1) summary
    pfam04923
    Location:14 → 117
    Ninjurin

  6. NM_001144570.1 → NP_001138042.1  ninjurin C, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001138042.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E2QD33
    Conserved Domains (1) summary
    pfam04923
    Location:14 → 114
    Ninjurin
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A8JQY7 A8JQY7
A8JQY8 A8JQY8
B7Z0S7 B7Z0S7
B7Z0S8 B7Z0S8
E2QD33 E2QD33
Q4V5X1 Q4V5X1

Gene LinkOut

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