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PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 [ Gallus gallus (chicken) ]

Gene ID: 415906, updated on 3-Dec-2024

Summary

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Official Symbol
PFKFB1provided by CGNC
Official Full Name
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1provided by CGNC
Primary source
CGNC:1494
See related
Ensembl:ENSGALG00010000402
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
PFK/FBPase; 6PF-2-K/Fru-2
Orthologs
human mouse all
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Genomic context

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See PFKFB1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Unplaced Scaffold NW_024096019.1 (6850..10815)

NW_024096019.1Genomic Context describing neighboring genes Neighboring gene N-alpha-acetyltransferase 10, NatA catalytic subunit Neighboring gene hydroxysteroid (17-beta) dehydrogenase 10 Neighboring gene NSE3 homolog, SMC5-SMC6 complex component Neighboring gene inter-alpha-trypsin inhibitor heavy chain family member 6 Neighboring gene G protein nucleolar 3 like Neighboring gene E3 ubiquitin-protein ligase HUWE1-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_024096019 Unplaced Scaffold Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Isolation of a cDNA for chicken liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Li L, et al. Biochem Biophys Res Commun, 1993 Jan 29. PMID 7916593
  2. An expressed sequence tag database of T-cell-enriched activated chicken splenocytes: sequence analysis of 5251 clones. Tirunagaru VG, et al. Genomics, 2000 Jun 1. PMID 10860659
  3. Chicken genomics resource: sequencing and annotation of 35,407 ESTs from single and multiple tissue cDNA libraries and CAP3 assembly of a chicken gene index. Carre W, et al. Physiol Genomics, 2006 May 16. PMID 16554550
  4. A comprehensive collection of chicken cDNAs. Boardman PE, et al. Curr Biol, 2002 Nov 19. PMID 12445392
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
Names
6PF-2-K/Fru-2,6-P2ase liver isozyme
NP_001348178.2
XP_025002044.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001361249.2 → NP_001348178.2  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase

    Status: VALIDATED

    Source sequence(s)
    AI982038, BG711308, BG712188, BU247029, BU442269, CN778689, JAENSK010000592
    UniProtKB/Swiss-Prot
    Q91348, Q9PWA7
    Related
    ENSGALP00010000414.1, ENSGALT00010000790.1

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NW_024096019.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    6850..10815
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025146276.3 → XP_025002044.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoform X1

    UniProtKB/Swiss-Prot
    Q91348, Q9PWA7
    Conserved Domains (2) summary
    pfam01591
    Location:11 → 229
    6PF2K; 6-phosphofructo-2-kinase
    pfam00300
    Location:232 → 418
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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