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ry - rosy

Enables xanthine dehydrogenase activity. Involved in several processes, including alpha-amino acid metabolic process; determination of adult lifespan; and nucleobase metabolic process. Is expressed in several structures, including adult head; endoderm anlage; germline cell; gut section; and mesoderm. Used to study xanthinuria. Human ortholog(s) of this gene implicated in several diseases, including Lesch-Nyhan syndrome; artery disease (multiple); chronic kidney disease; hyperuricemia; and xanthinuria type I. Orthologous to several human genes including XDH (xanthine dehydrogenase). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa