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CG11670 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41608, updated on 4-Jan-2025

Summary

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Official Symbol
CG11670provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0038114
Locus tag
Dmel_CG11670
See related
AllianceGenome:FB:FBgn0038114
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG11670; SP27
Summary
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Is expressed in embryonic central brain surface glial cell and lateral cord surface glial cell. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG11670 in Genome Data Viewer
Location:
87D9-87D9; 3-53 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (13042050..13044086)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8867772..8869808)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene rosy Neighboring gene uncharacterized protein Neighboring gene snake Neighboring gene uncharacterized protein Neighboring gene Heat shock protein 70 cognate 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Heat shock protein 83 (Hsp83) facilitates methoprene-tolerant (Met) nuclear import to modulate juvenile hormone signaling. He Q, et al. J Biol Chem, 2014 Oct 3. PMID 25122763, Free PMC Article
  2. A set of structural features defines the cis-regulatory modules of antenna-expressed genes in Drosophila melanogaster. López Y, et al. PLoS One, 2014. PMID 25153327, Free PMC Article
  3. Enhanced function annotations for Drosophila serine proteases: a case study for systematic annotation of multi-member gene families. Shah PK, et al. Gene, 2008 Jan 15. PMID 17996400
  4. Serine proteases and their homologs in the Drosophila melanogaster genome: an initial analysis of sequence conservation and phylogenetic relationships. Ross J, et al. Gene, 2003 Jan 30. PMID 12568721
  5. Building a platform for predicting functions of serine protease-related proteins in Drosophila melanogaster and other insects. Cao X, et al. Insect Biochem Mol Biol, 2018 Dec. PMID 30367934, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type endopeptidase activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
involved_in proteolysis ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG11670-PD
CG11670-PF
NP_001097767.2
NP_001368950.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    13042050..13044086
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001382016.1 → NP_001368950.1  uncharacterized protein Dmel_CG11670, isoform F [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A6F7RXE0, A8E756
    Conserved Domains (1) summary
    cd00190
    Location:172 → 419
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

  2. NM_001104297.4 → NP_001097767.2  uncharacterized protein Dmel_CG11670, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097767.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A8E756, A8JQZ4
    Conserved Domains (2) summary
    smart00020
    Location:145 → 389
    Tryp_SPc; Trypsin-like serine protease
    cd00190
    Location:145 → 392
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A6F7RXE0 A0A6F7RXE0
A8JQZ4 A8JQZ4

Gene LinkOut

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