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ERCC4 ERCC excision repair 4, endonuclease catalytic subunit [ Gallus gallus (chicken) ]

Gene ID: 416420, updated on 3-Dec-2024

Summary

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Symbol
ERCC4provided by CGNC
Full Name
ERCC excision repair 4, endonuclease catalytic subunitprovided by CGNC
Primary source
CGNC:2155
See related
Ensembl:ENSGALG00010020422
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
XPF
Orthologs
human mouse all
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Genomic context

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See ERCC4 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
12
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 14 NC_052545.1 (679496..692334)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 14 NC_052586.1 (678281..691119)

Chromosome 14 - NC_052545.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107054592 Neighboring gene shisa family member 9 Neighboring gene uncharacterized LOC107054591 Neighboring gene uncharacterized LOC121106794 Neighboring gene uncharacterized LOC107054576 Neighboring gene uncharacterized LOC107054578 Neighboring gene MKL1/myocardin like 2 Neighboring gene microRNA 6686

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structure-specific endonucleases xpf and mus81 play overlapping but essential roles in DNA repair by homologous recombination. Kikuchi K, et al. Cancer Res, 2013 Jul 15. PMID 23576554, Free PMC Article
  2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables damaged DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA endodeoxyribonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nucleotide-excision repair involved in interstrand cross-link repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in resolution of meiotic recombination intermediates IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of nucleotide-excision repair factor 1 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA repair endonuclease XPF
Names
excision repair cross-complementation group 4
excision repair cross-complementing rodent repair deficiency, complementation group 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001318411.2 → NP_001305340.2  DNA repair endonuclease XPF

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000257
    UniProtKB/TrEMBL
    A0A8V0ZKQ1, V5Y0M7
    Related
    ENSGALP00010029190.1, ENSGALT00010049381.1
    Conserved Domains (1) summary
    TIGR00596
    Location:86 → 894
    rad1; DNA repair protein (rad1)

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052545.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    679496..692334
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025155056.2 → XP_025010824.2  DNA repair endonuclease XPF isoform X1

    UniProtKB/TrEMBL
    V5Y0M7
    Conserved Domains (1) summary
    TIGR00596
    Location:1 → 724
    rad1; DNA repair protein (rad1)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052586.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    678281..691119
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046927325.1 → XP_046783281.1  DNA repair endonuclease XPF isoform X1

    UniProtKB/TrEMBL
    V5Y0M7
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Research Materials