Adgf-D Adenosine deaminase-related growth factor D [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Adgf-Dprovided by FlyBase
Official Full Name: Adenosine deaminase-related growth factor Dprovided by FlyBase
Primary source: FLYBASE:FBgn0038172
Locus tag: Dmel_CG9621
See related: AllianceGenome:FB:FBgn0038172
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: ADGF-D; adgfd; AdgfD; ADGFD; CG9621; Dmel\CG9621
Summary: Enables adenosine deaminase activity. Involved in adenosine catabolic process and positive regulation of cell population proliferation. Located in extracellular space. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in Sneddon syndrome. Orthologous to human ADA2 (adenosine deaminase 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (13703084..13705402, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (9528806..9531124, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables adenosine deaminase activity	IBA Inferred from Biological aspect of Ancestor more info
enables adenosine deaminase activity	IDA Inferred from Direct Assay more info	PubMed
enables adenosine deaminase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in adenosine catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in adenosine catabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in adenosine catabolic process	IEA Inferred from Electronic Annotation more info
involved_in inosine biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of cell population proliferation	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info
located_in extracellular space	IDA Inferred from Direct Assay more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info

NP_524345.2

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The following sections contain reference sequences that belong to a specific genome build. Explain