U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ubc87F Ubiquitin conjugating enzyme 87F [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41682, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
Ubc87Fprovided by FlyBase
Official Full Name
Ubiquitin conjugating enzyme 87Fprovided by FlyBase
Primary source
FLYBASE:FBgn0267383
Locus tag
Dmel_CG9602
See related
AllianceGenome:FB:FBgn0267383
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
83A; AT76; BcDNA:GH25305; CG9602; Dmel\CG9602; UBC; Ubc87Fb; Ube2G1
Summary
Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein polyubiquitination. Orthologous to human UBE2G1 (ubiquitin conjugating enzyme E2 G1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Ubc87F in Genome Data Viewer
Location:
87F12-87F12; 3-54 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (13717454..13718176, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (9543176..9543898, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR34044 Neighboring gene primo-1 Neighboring gene primo-2 Neighboring gene kramer Neighboring gene uncharacterized protein Neighboring gene Chitinase 5

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The Drosophila primo locus encodes two low-molecular-weight tyrosine phosphatases. Miller DT, et al. Gene, 2000 Feb 8. PMID 10675607
  2. UbcD4, an ortholog of E2-25K/Ube2K, is essential for activation of the immune deficiency pathway in Drosophila. Park ES, et al. Biochem Biophys Res Commun, 2016 Jan 22. PMID 26707646
  3. Functional and phylogenetic analysis of the ubiquitylation system in Caenorhabditis elegans: ubiquitin-conjugating enzymes, ubiquitin-activating enzymes, and ubiquitin-like proteins. Jones D, et al. Genome Biol, 2002. PMID 11806825, Free PMC Article
  4. What was the set of ubiquitin and ubiquitin-like conjugating enzymes in the eukaryote common ancestor? Michelle C, et al. J Mol Evol, 2009 Jun. PMID 19452197, Free PMC Article
  5. Comparative genomics reveals a constant rate of origination and convergent acquisition of functional retrogenes in Drosophila. Bai Y, et al. Genome Biol, 2007. PMID 17233920, Free PMC Article

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ubiquitin conjugating enzyme activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin-protein transferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein polyubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein polyubiquitination ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

Go to the top of the page Help
Preferred Names
ubiquitin conjugating enzyme 87F
Names
CG9602-PA
Ubc87F-PA
ubiquitin conjugating enzyme 87Fb
NP_650309.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    13717454..13718176 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142052.2 → NP_650309.1  ubiquitin conjugating enzyme 87F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650309.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IH42, Q9VFR8
    Related
    FBpp0082303
    Conserved Domains (2) summary
    COG5078
    Location:1 → 163
    COG5078; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
    pfam00179
    Location:10 → 160
    UQ_con; Ubiquitin-conjugating enzyme
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8IH42 Q8IH42
Q9VFR8 Q9VFR8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools