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EGFL7 EGF like domain multiple 7 [ Gallus gallus (chicken) ]

Gene ID: 417137, updated on 3-Dec-2024

Summary

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Symbol
EGFL7provided by CGNC
Full Name
EGF like domain multiple 7provided by CGNC
Primary source
CGNC:1724
See related
Ensembl:ENSGALG00010028919
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See EGFL7 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
13
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 17 NC_052548.1 (8352238..8366866, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 17 NC_052589.1 (7763517..7778150, complement)

Chromosome 17 - NC_052548.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 69 member B Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase 2 Neighboring gene microRNA 126 Neighboring gene notch 1 Neighboring gene SEC16 homolog A, endoplasmic reticulum export factor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in anatomical structure development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
epidermal growth factor-like protein 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001305681.2 → NP_001292610.2  epidermal growth factor-like protein 7 precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000308
    UniProtKB/TrEMBL
    A0A8V1AI82, A0A8V1AM60
    Related
    ENSGALP00010043093.1, ENSGALT00010069967.1
    Conserved Domains (3) summary
    cd00054
    Location:111 → 136
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cl00057
    Location:135 → 176
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    cl40670
    Location:198 → 222
    PCRF; PCRF domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052548.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    8352238..8366866 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025156056.3 → XP_025011824.2  epidermal growth factor-like protein 7 isoform X1

    UniProtKB/TrEMBL
    A0A8V1AI82, A0A8V1AM60
    Conserved Domains (3) summary
    cd00054
    Location:111 → 136
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cl00057
    Location:135 → 176
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    cl40670
    Location:198 → 222
    PCRF; PCRF domain

  2. XM_040649054.2 → XP_040504988.1  epidermal growth factor-like protein 7 isoform X1

    UniProtKB/TrEMBL
    A0A8V1AI82, A0A8V1AM60
    Conserved Domains (3) summary
    cd00054
    Location:111 → 136
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cl00057
    Location:135 → 176
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    cl40670
    Location:198 → 222
    PCRF; PCRF domain

  3. XM_040649055.2 → XP_040504989.1  epidermal growth factor-like protein 7 isoform X2

    Conserved Domains (2) summary
    cd00054
    Location:111 → 136
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cl00057
    Location:135 → 176
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052589.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    7763517..7778150 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046928912.1 → XP_046784868.1  epidermal growth factor-like protein 7 isoform X1

    UniProtKB/TrEMBL
    A0A8V1AI82, A0A8V1AM60

  2. XM_046928913.1 → XP_046784869.1  epidermal growth factor-like protein 7 isoform X1

    UniProtKB/TrEMBL
    A0A8V1AI82, A0A8V1AM60

  3. XM_046928914.1 → XP_046784870.1  epidermal growth factor-like protein 7 isoform X2

Nucleotide Protein Strain
Heading Accession and Version

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