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NTN4 netrin 4 [ Gallus gallus (chicken) ]

Gene ID: 417914, updated on 3-Dec-2024

Summary

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Symbol
NTN4provided by CGNC
Full Name
netrin 4provided by CGNC
Primary source
CGNC:8669
See related
Ensembl:ENSGALG00010011859
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
netrin-4
Orthologs
human mouse all
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Genomic context

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See NTN4 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
11
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (45649593..45685920, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (46001132..46037460, complement)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene methionyl aminopeptidase 2 Neighboring gene ubiquitin specific peptidase 44 Neighboring gene small nuclear ribonucleoprotein polypeptide F Neighboring gene amidohydrolase domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in basement membrane assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in substrate adhesion-dependent cell spreading IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of laminin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
netrin-4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    45649593..45685920 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015283916.4 → XP_015139402.2  netrin-4 isoform X2

    UniProtKB/TrEMBL
    A0A8V0YJJ8
    Conserved Domains (4) summary
    smart00180
    Location:393 → 444
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:259 → 318
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd03578
    Location:514 → 624
    NTR_netrin-4_like; NTR domain, Netrin-4-like subfamily; composed of the C-terminal NTR domains of netrin-4 (beta netrin) and similar proteins. Netrins are secreted proteins that function as tropic cues in the direction of axon growth and cell migration during neural ...
    cl02806
    Location:30 → 258
    Laminin_N; Laminin N-terminal (Domain VI)

  2. XM_004937645.5 → XP_004937702.3  netrin-4 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y6F0, A0A8V0YJJ8
    Related
    ENSGALP00010016230.1, ENSGALT00010028328.1
    Conserved Domains (4) summary
    smart00180
    Location:393 → 444
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:259 → 318
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd03578
    Location:515 → 625
    NTR_netrin-4_like; NTR domain, Netrin-4-like subfamily; composed of the C-terminal NTR domains of netrin-4 (beta netrin) and similar proteins. Netrins are secreted proteins that function as tropic cues in the direction of axon growth and cell migration during neural ...
    cl02806
    Location:30 → 258
    Laminin_N; Laminin N-terminal (Domain VI)

  3. XM_046909072.1 → XP_046765028.1  netrin-4 isoform X4

    UniProtKB/TrEMBL
    A0A8V0YJJ8

  4. XM_004937647.5 → XP_004937704.3  netrin-4 isoform X3

    UniProtKB/TrEMBL
    A0A8V0Y6E6, A0A8V0YJJ8
    Related
    ENSGALP00010016225.1, ENSGALT00010028323.1
    Conserved Domains (4) summary
    smart00180
    Location:383 → 434
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:249 → 308
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd03578
    Location:505 → 615
    NTR_netrin-4_like; NTR domain, Netrin-4-like subfamily; composed of the C-terminal NTR domains of netrin-4 (beta netrin) and similar proteins. Netrins are secreted proteins that function as tropic cues in the direction of axon growth and cell migration during neural ...
    cl02806
    Location:20 → 248
    Laminin_N; Laminin N-terminal (Domain VI)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    46001132..46037460 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040660028.2 → XP_040515962.1  netrin-4 isoform X2

    UniProtKB/TrEMBL
    A0A8V0YJJ8
    Conserved Domains (4) summary
    smart00180
    Location:393 → 444
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:259 → 318
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd03578
    Location:514 → 624
    NTR_netrin-4_like; NTR domain, Netrin-4-like subfamily; composed of the C-terminal NTR domains of netrin-4 (beta netrin) and similar proteins. Netrins are secreted proteins that function as tropic cues in the direction of axon growth and cell migration during neural ...
    cl02806
    Location:30 → 258
    Laminin_N; Laminin N-terminal (Domain VI)

  2. XM_040660027.2 → XP_040515961.1  netrin-4 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y6F0, A0A8V0YJJ8
    Conserved Domains (4) summary
    smart00180
    Location:393 → 444
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:259 → 318
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd03578
    Location:515 → 625
    NTR_netrin-4_like; NTR domain, Netrin-4-like subfamily; composed of the C-terminal NTR domains of netrin-4 (beta netrin) and similar proteins. Netrins are secreted proteins that function as tropic cues in the direction of axon growth and cell migration during neural ...
    cl02806
    Location:30 → 258
    Laminin_N; Laminin N-terminal (Domain VI)

  3. XM_046909474.1 → XP_046765430.1  netrin-4 isoform X4

    UniProtKB/TrEMBL
    A0A8V0YJJ8

  4. XM_040660029.2 → XP_040515963.1  netrin-4 isoform X3

    UniProtKB/TrEMBL
    A0A8V0Y6E6, A0A8V0YJJ8
    Conserved Domains (4) summary
    smart00180
    Location:383 → 434
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    cd00055
    Location:249 → 308
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd03578
    Location:505 → 615
    NTR_netrin-4_like; NTR domain, Netrin-4-like subfamily; composed of the C-terminal NTR domains of netrin-4 (beta netrin) and similar proteins. Netrins are secreted proteins that function as tropic cues in the direction of axon growth and cell migration during neural ...
    cl02806
    Location:20 → 248
    Laminin_N; Laminin N-terminal (Domain VI)
Nucleotide Protein
Heading Accession and Version

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