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MKL1 megakaryoblastic leukemia (translocation) 1 [ Gallus gallus (chicken) ]

Gene ID: 418005, updated on 26-Jan-2025

Summary

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Symbol
MKL1provided by CGNC
Full Name
megakaryoblastic leukemia (translocation) 1provided by CGNC
Primary source
CGNC:9114
See related
Ensembl:ENSGALG00010013053
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See MKL1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
19
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (50003390..50101264)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (50300314..50398221)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudogene 5 Neighboring gene solute carrier family 25 member 17 Neighboring gene uncharacterized LOC101749282 Neighboring gene small G protein signaling modulator 3 Neighboring gene adenylosuccinate lyase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in smooth muscle cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
MKL/myocardin-like protein 1; myocardin-related transcription factor A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001436083.1 → NP_001423012.1  MKL/myocardin-like protein 1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000012

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    50003390..50101264
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046907698.1 → XP_046763654.1  myocardin-related transcription factor A isoform X3

    UniProtKB/TrEMBL
    A0A8V0YBV0

  2. XM_046907709.1 → XP_046763665.1  myocardin-related transcription factor A isoform X3

    UniProtKB/TrEMBL
    A0A8V0YBV0

  3. XM_416243.8 → XP_416243.4  myocardin-related transcription factor A isoform X3

    UniProtKB/TrEMBL
    A0A8V0YBV0
    Related
    ENSGALP00010018282.1, ENSGALT00010031348.1
    Conserved Domains (3) summary
    smart00707
    Location:24 → 49
    RPEL; Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2
    PLN03124
    Location:299 → 418
    PLN03124; poly [ADP-ribose] polymerase; Provisional
    pfam02037
    Location:349 → 382
    SAP; SAP domain

  4. XM_004937714.4 → XP_004937771.1  myocardin-related transcription factor A isoform X2

    UniProtKB/TrEMBL
    A0A8V0YBV0
    Related
    ENSGALP00010018245.1, ENSGALT00010031299.1
    Conserved Domains (3) summary
    smart00707
    Location:62 → 87
    RPEL; Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2
    PLN03124
    Location:337 → 456
    PLN03124; poly [ADP-ribose] polymerase; Provisional
    pfam02037
    Location:387 → 420
    SAP; SAP domain

  5. XM_004937713.5 → XP_004937770.1  myocardin-related transcription factor A isoform X1

    UniProtKB/TrEMBL
    A0A8V0YBV0, A0A8V0YI87
    Related
    ENSGALP00010018252.1, ENSGALT00010031308.1
    Conserved Domains (3) summary
    smart00707
    Location:86 → 111
    RPEL; Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2
    PLN03124
    Location:361 → 480
    PLN03124; poly [ADP-ribose] polymerase; Provisional
    pfam02037
    Location:411 → 444
    SAP; SAP domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    50300314..50398221
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046910040.1 → XP_046765996.1  myocardin-related transcription factor A isoform X3

    UniProtKB/TrEMBL
    A0A8V0YBV0

  2. XM_046910041.1 → XP_046765997.1  myocardin-related transcription factor A isoform X3

    UniProtKB/TrEMBL
    A0A8V0YBV0

  3. XM_040660609.2 → XP_040516543.1  myocardin-related transcription factor A isoform X3

    UniProtKB/TrEMBL
    A0A8V0YBV0
    Conserved Domains (3) summary
    smart00707
    Location:24 → 49
    RPEL; Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2
    PLN03124
    Location:299 → 418
    PLN03124; poly [ADP-ribose] polymerase; Provisional
    pfam02037
    Location:349 → 382
    SAP; SAP domain

  4. XM_040660608.2 → XP_040516542.1  myocardin-related transcription factor A isoform X4

    UniProtKB/TrEMBL
    A0A8V0YBV0, A0A8V0YKA2
    Conserved Domains (3) summary
    smart00707
    Location:59 → 84
    RPEL; Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2
    PLN03124
    Location:334 → 453
    PLN03124; poly [ADP-ribose] polymerase; Provisional
    pfam02037
    Location:384 → 417
    SAP; SAP domain

  5. XM_040660607.2 → XP_040516541.1  myocardin-related transcription factor A isoform X2

    UniProtKB/TrEMBL
    A0A8V0YBV0
    Conserved Domains (3) summary
    smart00707
    Location:62 → 87
    RPEL; Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2
    PLN03124
    Location:337 → 456
    PLN03124; poly [ADP-ribose] polymerase; Provisional
    pfam02037
    Location:387 → 420
    SAP; SAP domain

  6. XM_040660606.2 → XP_040516540.1  myocardin-related transcription factor A isoform X1

    UniProtKB/TrEMBL
    A0A8V0YBV0, A0A8V0YI87
    Conserved Domains (3) summary
    smart00707
    Location:86 → 111
    RPEL; Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2
    PLN03124
    Location:361 → 480
    PLN03124; poly [ADP-ribose] polymerase; Provisional
    pfam02037
    Location:411 → 444
    SAP; SAP domain
Nucleotide Protein
Heading Accession and Version

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