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LAG3 lymphocyte activating 3 [ Gallus gallus (chicken) ]

Gene ID: 418287, updated on 17-Aug-2024

Summary

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Symbol
LAG3provided by CGNC
Full Name
lymphocyte activating 3provided by CGNC
Primary source
CGNC:10763
See related
Ensembl:ENSGALG00010023324
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See LAG3 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
8
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (77145812..77151401)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (77346083..77352115)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100859057 Neighboring gene parathymosin Neighboring gene CD4 molecule Neighboring gene G protein-coupled receptor 162

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables MHC class II protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in T cell activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in interleukin-15-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
lymphocyte activation gene 3 protein
Names
lymphocyte-activation gene 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    77145812..77151401
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_416510.7 → XP_416510.3  lymphocyte activation gene 3 protein isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZMF0
    Related
    ENSGALP00010034564.1, ENSGALT00010056851.1
    Conserved Domains (2) summary
    smart00409
    Location:243 → 331
    IG; Immunoglobulin
    cl11960
    Location:41 → 128
    Ig; Immunoglobulin domain

  2. XM_025143029.3 → XP_024998797.2  lymphocyte activation gene 3 protein isoform X2

    Conserved Domains (2) summary
    smart00409
    Location:242 → 330
    IG; Immunoglobulin
    cl11960
    Location:40 → 127
    Ig; Immunoglobulin domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    77346083..77352115
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040661606.2 → XP_040517540.1  lymphocyte activation gene 3 protein isoform X2

    Conserved Domains (2) summary
    smart00409
    Location:242 → 330
    IG; Immunoglobulin
    cl11960
    Location:40 → 127
    Ig; Immunoglobulin domain

  2. XM_040661605.2 → XP_040517539.1  lymphocyte activation gene 3 protein isoform X1

    Conserved Domains (2) summary
    smart00409
    Location:243 → 331
    IG; Immunoglobulin
    cl11960
    Location:41 → 128
    Ig; Immunoglobulin domain
Nucleotide Protein
Heading Accession and Version

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