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TTC3 tetratricopeptide repeat domain 3 [ Gallus gallus (chicken) ]

Gene ID: 418518, updated on 17-Aug-2024

Summary

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Symbol
TTC3provided by CGNC
Full Name
tetratricopeptide repeat domain 3provided by CGNC
Primary source
CGNC:11990
See related
Ensembl:ENSGALG00010013135
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See TTC3 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
48
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (107094291..107154237)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (107183798..107243747)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene ripply transcriptional repressor 3 Neighboring gene phosphatidylinositol glycan anchor biosynthesis class P Neighboring gene DSCR3 arrestin fold containing Neighboring gene uncharacterized LOC121107521

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase TTC3
XP_015156894.1
XP_015156902.1
XP_015156908.1
XP_015156915.1
XP_015156920.1
XP_015156926.2
XP_025001034.1
XP_040508021.1
XP_040515568.1
XP_040515569.1
XP_040515570.1
XP_040515571.1
XP_040515572.1
XP_040515573.1
XP_040515574.1
XP_040515576.1
XP_040515578.1
XP_046761609.1
XP_046761611.1
XP_046761614.1
XP_046761617.1
XP_046761620.1
XP_046765641.1
XP_046765642.1
XP_046765643.1
XP_046765644.1
XP_046765645.1
XP_416727.4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    107094291..107154237
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_416727.8 → XP_416727.4  E3 ubiquitin-protein ligase TTC3 isoform X1

    Conserved Domains (4) summary
    cd00162
    Location:1920 → 1963
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    sd00006
    Location:212 → 240
    TPR; TPR repeat [structural motif]
    pfam12678
    Location:1917 → 1960
    zf-rbx1; RING-H2 zinc finger
    pfam13414
    Location:211 → 277
    TPR_11; TPR repeat

  2. XM_015301408.4 → XP_015156894.1  E3 ubiquitin-protein ligase TTC3 isoform X2

    Conserved Domains (4) summary
    cd00162
    Location:1919 → 1962
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    sd00006
    Location:211 → 239
    TPR; TPR repeat [structural motif]
    pfam12678
    Location:1916 → 1959
    zf-rbx1; RING-H2 zinc finger
    pfam13414
    Location:210 → 276
    TPR_11; TPR repeat

  3. XM_046905661.1 → XP_046761617.1  E3 ubiquitin-protein ligase TTC3 isoform X6

  4. XM_046905655.1 → XP_046761611.1  E3 ubiquitin-protein ligase TTC3 isoform X6

  5. XM_015301422.4 → XP_015156908.1  E3 ubiquitin-protein ligase TTC3 isoform X3

    UniProtKB/TrEMBL
    F1P0T0
    Conserved Domains (4) summary
    cd00162
    Location:1912 → 1955
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    sd00006
    Location:204 → 232
    TPR; TPR repeat [structural motif]
    pfam12678
    Location:1909 → 1952
    zf-rbx1; RING-H2 zinc finger
    pfam13414
    Location:203 → 269
    TPR_11; TPR repeat

  6. XM_025145266.3 → XP_025001034.1  E3 ubiquitin-protein ligase TTC3 isoform X4

    Conserved Domains (5) summary
    COG5574
    Location:1781 → 1905
    PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    sd00006
    Location:149 → 177
    TPR; TPR repeat [structural motif]
    cd16481
    Location:1856 → 1897
    RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins
    cl25732
    Location:1347 → 1602
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26005
    Location:135 → 284
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional

  7. XM_015301434.4 → XP_015156920.1  E3 ubiquitin-protein ligase TTC3 isoform X5

    UniProtKB/TrEMBL
    A0A8V0YQG6
    Related
    ENSGALP00010018411.1, ENSGALT00010031521.1
    Conserved Domains (4) summary
    cd00162
    Location:1856 → 1899
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    sd00006
    Location:148 → 176
    TPR; TPR repeat [structural motif]
    pfam12678
    Location:1853 → 1896
    zf-rbx1; RING-H2 zinc finger
    pfam13414
    Location:147 → 213
    TPR_11; TPR repeat

  8. XM_015301416.4 → XP_015156902.1  E3 ubiquitin-protein ligase TTC3 isoform X3

    UniProtKB/TrEMBL
    F1P0T0
    Related
    ENSGALP00010018436.1, ENSGALT00010031560.1
    Conserved Domains (4) summary
    cd00162
    Location:1912 → 1955
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    sd00006
    Location:204 → 232
    TPR; TPR repeat [structural motif]
    pfam12678
    Location:1909 → 1952
    zf-rbx1; RING-H2 zinc finger
    pfam13414
    Location:203 → 269
    TPR_11; TPR repeat

  9. XM_040652087.2 → XP_040508021.1  E3 ubiquitin-protein ligase TTC3 isoform X6

    Conserved Domains (6) summary
    COG1196
    Location:1196 → 1451
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG5574
    Location:1630 → 1754
    PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    TIGR00990
    Location:1 → 133
    3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
    sd00006
    Location:1 → 26
    TPR; TPR repeat [structural motif]
    cd16481
    Location:1705 → 1746
    RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins
    pfam19179
    Location:396 → 511
    DUF5861; Family of unknown function (DUF5861)

  10. XM_046905664.1 → XP_046761620.1  E3 ubiquitin-protein ligase TTC3 isoform X6

  11. XM_046905658.1 → XP_046761614.1  E3 ubiquitin-protein ligase TTC3 isoform X6

  12. XM_015301429.4 → XP_015156915.1  E3 ubiquitin-protein ligase TTC3 isoform X3

    UniProtKB/TrEMBL
    F1P0T0
    Conserved Domains (4) summary
    cd00162
    Location:1912 → 1955
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    sd00006
    Location:204 → 232
    TPR; TPR repeat [structural motif]
    pfam12678
    Location:1909 → 1952
    zf-rbx1; RING-H2 zinc finger
    pfam13414
    Location:203 → 269
    TPR_11; TPR repeat

  13. XM_046905653.1 → XP_046761609.1  E3 ubiquitin-protein ligase TTC3 isoform X6

  14. XM_015301440.4 → XP_015156926.2  E3 ubiquitin-protein ligase TTC3 isoform X7

    Conserved Domains (3) summary
    COG1196
    Location:1044 → 1299
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG5574
    Location:1478 → 1602
    PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    cd16481
    Location:1553 → 1594
    RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    107183798..107243747
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040659634.2 → XP_040515568.1  E3 ubiquitin-protein ligase TTC3 isoform X1

    Conserved Domains (5) summary
    COG1196
    Location:1410 → 1665
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG5574
    Location:1844 → 1968
    PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    TIGR00990
    Location:198 → 347
    3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
    sd00006
    Location:212 → 240
    TPR; TPR repeat [structural motif]
    cd16481
    Location:1919 → 1960
    RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins

  2. XM_040659635.2 → XP_040515569.1  E3 ubiquitin-protein ligase TTC3 isoform X2

    Conserved Domains (5) summary
    COG1196
    Location:1409 → 1664
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG5574
    Location:1843 → 1967
    PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    TIGR00990
    Location:197 → 346
    3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
    sd00006
    Location:211 → 239
    TPR; TPR repeat [structural motif]
    cd16481
    Location:1918 → 1959
    RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins

  3. XM_046909688.1 → XP_046765644.1  E3 ubiquitin-protein ligase TTC3 isoform X6

  4. XM_046909686.1 → XP_046765642.1  E3 ubiquitin-protein ligase TTC3 isoform X6

  5. XM_040659637.2 → XP_040515571.1  E3 ubiquitin-protein ligase TTC3 isoform X3

    Conserved Domains (5) summary
    COG1196
    Location:1402 → 1657
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG5574
    Location:1836 → 1960
    PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    TIGR00990
    Location:190 → 339
    3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
    sd00006
    Location:204 → 232
    TPR; TPR repeat [structural motif]
    cd16481
    Location:1911 → 1952
    RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins

  6. XM_040659639.2 → XP_040515573.1  E3 ubiquitin-protein ligase TTC3 isoform X4

    Conserved Domains (5) summary
    COG1196
    Location:1347 → 1602
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG5574
    Location:1781 → 1905
    PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    TIGR00990
    Location:135 → 284
    3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
    sd00006
    Location:149 → 177
    TPR; TPR repeat [structural motif]
    cd16481
    Location:1856 → 1897
    RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins

  7. XM_040659640.2 → XP_040515574.1  E3 ubiquitin-protein ligase TTC3 isoform X5

    Conserved Domains (5) summary
    COG1196
    Location:1346 → 1601
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG5574
    Location:1780 → 1904
    PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    TIGR00990
    Location:134 → 283
    3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
    sd00006
    Location:148 → 176
    TPR; TPR repeat [structural motif]
    cd16481
    Location:1855 → 1896
    RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins

  8. XM_040659636.2 → XP_040515570.1  E3 ubiquitin-protein ligase TTC3 isoform X3

    Conserved Domains (5) summary
    COG1196
    Location:1402 → 1657
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG5574
    Location:1836 → 1960
    PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    TIGR00990
    Location:190 → 339
    3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
    sd00006
    Location:204 → 232
    TPR; TPR repeat [structural motif]
    cd16481
    Location:1911 → 1952
    RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins

  9. XM_040659642.2 → XP_040515576.1  E3 ubiquitin-protein ligase TTC3 isoform X6

    Conserved Domains (5) summary
    COG1196
    Location:1196 → 1451
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG5574
    Location:1630 → 1754
    PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    TIGR00990
    Location:1 → 133
    3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
    sd00006
    Location:1 → 26
    TPR; TPR repeat [structural motif]
    cd16481
    Location:1705 → 1746
    RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins

  10. XM_046909689.1 → XP_046765645.1  E3 ubiquitin-protein ligase TTC3 isoform X6

  11. XM_046909687.1 → XP_046765643.1  E3 ubiquitin-protein ligase TTC3 isoform X6

  12. XM_040659638.2 → XP_040515572.1  E3 ubiquitin-protein ligase TTC3 isoform X3

    Conserved Domains (5) summary
    COG1196
    Location:1402 → 1657
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG5574
    Location:1836 → 1960
    PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    TIGR00990
    Location:190 → 339
    3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)
    sd00006
    Location:204 → 232
    TPR; TPR repeat [structural motif]
    cd16481
    Location:1911 → 1952
    RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins

  13. XM_046909685.1 → XP_046765641.1  E3 ubiquitin-protein ligase TTC3 isoform X6

  14. XM_040659644.2 → XP_040515578.1  E3 ubiquitin-protein ligase TTC3 isoform X7

    Conserved Domains (3) summary
    COG1196
    Location:1044 → 1299
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG5574
    Location:1478 → 1602
    PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
    cd16481
    Location:1553 → 1594
    RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins
Nucleotide Protein
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