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CASK calcium/calmodulin dependent serine protein kinase [ Gallus gallus (chicken) ]

Gene ID: 418565, updated on 17-Aug-2024

Summary

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Official Symbol
CASKprovided by CGNC
Official Full Name
calcium/calmodulin dependent serine protein kinaseprovided by CGNC
Primary source
CGNC:12132
See related
Ensembl:ENSGALG00010002424
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See CASK in Genome Data Viewer
Location:
chromosome: 1
Exon count:
29
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (111886733..112082128)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (111940517..112136322)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101749987 Neighboring gene uncharacterized LOC112531051 Neighboring gene uncharacterized LOC101750030 Neighboring gene G protein-coupled receptor 82 Neighboring gene G protein-coupled receptor 34 Neighboring gene uncharacterized LOC121109949 Neighboring gene uncharacterized LOC101750611 Neighboring gene nyctalopin Neighboring gene DEAD-box helicase 3X

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of neurotransmitter secretion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basolateral plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
peripheral plasma membrane protein CASK
Names
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
XP_015157125.1
XP_015157131.1
XP_015157135.1
XP_015157141.1
XP_015157146.1
XP_025001723.1
XP_025001724.1
XP_025001725.1
XP_025001726.1
XP_025001733.1
XP_025001737.1
XP_025001743.1
XP_040517710.1
XP_040517711.1
XP_040517712.1
XP_040517713.1
XP_040517714.1
XP_040517715.1
XP_040517716.1
XP_040517717.1
XP_040517718.1
XP_040517719.1
XP_040517720.1
XP_040517721.1
XP_040517722.1
XP_040520802.1
XP_046765792.1
XP_046767419.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    111886733..112082128
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015301649.4 → XP_015157135.1  peripheral plasma membrane protein CASK isoform X1

    UniProtKB/TrEMBL
    A0A1D5PB73, A0A8V0X9W6
    Related
    ENSGALP00010003425.1, ENSGALT00010005586.1
    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:616 → 677
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:738 → 911
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  2. XM_015301645.4 → XP_015157131.1  peripheral plasma membrane protein CASK isoform X2

    UniProtKB/TrEMBL
    A0A8V0X9W6
    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:616 → 677
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:733 → 906
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  3. XM_025145956.3 → XP_025001724.1  peripheral plasma membrane protein CASK isoform X4

    UniProtKB/TrEMBL
    A0A8V0X9W6
    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:604 → 665
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:726 → 899
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  4. XM_025145957.3 → XP_025001725.1  peripheral plasma membrane protein CASK isoform X5

    UniProtKB/TrEMBL
    A0A8V0X9W6
    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:604 → 665
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:721 → 894
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  5. XM_025145958.3 → XP_025001726.1  peripheral plasma membrane protein CASK isoform X7

    UniProtKB/TrEMBL
    A0A8V0X9W6, A0A8V0XCV3
    Related
    ENSGALP00010003422.1, ENSGALT00010005583.1
    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:593 → 654
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:715 → 888
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  6. XM_015301655.4 → XP_015157141.1  peripheral plasma membrane protein CASK isoform X8

    UniProtKB/TrEMBL
    A0A8V0X9W6
    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:593 → 654
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:710 → 883
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  7. XM_025145965.3 → XP_025001733.1  peripheral plasma membrane protein CASK isoform X10

    UniProtKB/TrEMBL
    A0A8V0X9W6
    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:581 → 642
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:703 → 876
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  8. XM_025145955.3 → XP_025001723.1  peripheral plasma membrane protein CASK isoform X3

    UniProtKB/TrEMBL
    A0A3Q2UPZ2, A0A8V0X9W6
    Related
    ENSGALP00010003429.1, ENSGALT00010005590.1
    Conserved Domains (6) summary
    smart00569
    Location:342 → 395
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:610 → 671
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:482 → 562
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:732 → 905
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:400 → 450
    L27; L27 domain

  9. XM_040664868.2 → XP_040520802.1  peripheral plasma membrane protein CASK isoform X6

    UniProtKB/TrEMBL
    A0A8V0X5T9, A0A8V0X9W6
    Related
    ENSGALP00010003430.1, ENSGALT00010005591.1
    Conserved Domains (6) summary
    smart00569
    Location:342 → 395
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:598 → 659
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:482 → 562
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:720 → 893
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:400 → 450
    L27; L27 domain

  10. XM_015301660.4 → XP_015157146.1  peripheral plasma membrane protein CASK isoform X9

    UniProtKB/TrEMBL
    A0A8V0X9W6
    Conserved Domains (6) summary
    smart00569
    Location:342 → 395
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:587 → 648
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:482 → 562
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:709 → 882
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:400 → 450
    L27; L27 domain

  11. XM_025145969.3 → XP_025001737.1  peripheral plasma membrane protein CASK isoform X11

    UniProtKB/TrEMBL
    A0A8V0X9W6
    Related
    ENSGALP00010003433.1, ENSGALT00010005594.1
    Conserved Domains (6) summary
    smart00569
    Location:342 → 395
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:575 → 636
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:482 → 562
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:692 → 865
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:400 → 450
    L27; L27 domain

  12. XM_025145975.2 → XP_025001743.1  peripheral plasma membrane protein CASK isoform X12

    Conserved Domains (6) summary
    smart00569
    Location:163 → 216
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12035
    Location:431 → 492
    SH3_MPP1-like; Src Homology 3 domain of Membrane Protein, Palmitoylated 1 (or MAGUK p55 subfamily member 1)-like proteins
    cd00992
    Location:303 → 383
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:553 → 726
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:221 → 271
    L27; L27 domain
    cl21453
    Location:1 → 122
    PKc_like; Protein Kinases, catalytic domain

  13. XM_046911463.1 → XP_046767419.1  peripheral plasma membrane protein CASK isoform X13

  14. XM_015301639.4 → XP_015157125.1  peripheral plasma membrane protein CASK isoform X13

    Conserved Domains (3) summary
    cd12035
    Location:179 → 240
    SH3_MPP1-like; Src Homology 3 domain of Membrane Protein, Palmitoylated 1 (or MAGUK p55 subfamily member 1)-like proteins
    cd00992
    Location:51 → 131
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:301 → 474
    Guanylate_kin; Guanylate kinase

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    111940517..112136322
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040661776.2 → XP_040517710.1  peripheral plasma membrane protein CASK isoform X1

    UniProtKB/TrEMBL
    A0A1D5PB73, A0A8V0X9W6
    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:616 → 677
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:738 → 911
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  2. XM_040661777.2 → XP_040517711.1  peripheral plasma membrane protein CASK isoform X2

    UniProtKB/TrEMBL
    A0A8V0X9W6
    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:616 → 677
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:733 → 906
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  3. XM_040661779.2 → XP_040517713.1  peripheral plasma membrane protein CASK isoform X4

    UniProtKB/TrEMBL
    A0A8V0X9W6
    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:604 → 665
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:726 → 899
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  4. XM_040661780.2 → XP_040517714.1  peripheral plasma membrane protein CASK isoform X5

    UniProtKB/TrEMBL
    A0A8V0X9W6
    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:604 → 665
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:721 → 894
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  5. XM_040661782.2 → XP_040517716.1  peripheral plasma membrane protein CASK isoform X7

    UniProtKB/TrEMBL
    A0A8V0X9W6, A0A8V0XCV3
    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:593 → 654
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:715 → 888
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  6. XM_040661783.2 → XP_040517717.1  peripheral plasma membrane protein CASK isoform X8

    UniProtKB/TrEMBL
    A0A8V0X9W6
    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:593 → 654
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:710 → 883
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  7. XM_040661785.2 → XP_040517719.1  peripheral plasma membrane protein CASK isoform X10

    UniProtKB/TrEMBL
    A0A8V0X9W6
    Conserved Domains (6) summary
    smart00569
    Location:348 → 401
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:581 → 642
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:488 → 568
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:703 → 876
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:406 → 456
    L27; L27 domain

  8. XM_040661778.2 → XP_040517712.1  peripheral plasma membrane protein CASK isoform X3

    UniProtKB/TrEMBL
    A0A3Q2UPZ2, A0A8V0X9W6
    Conserved Domains (6) summary
    smart00569
    Location:342 → 395
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:610 → 671
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:482 → 562
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:732 → 905
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:400 → 450
    L27; L27 domain

  9. XM_040661781.2 → XP_040517715.1  peripheral plasma membrane protein CASK isoform X6

    UniProtKB/TrEMBL
    A0A8V0X5T9, A0A8V0X9W6
    Conserved Domains (6) summary
    smart00569
    Location:342 → 395
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:598 → 659
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:482 → 562
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:720 → 893
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:400 → 450
    L27; L27 domain

  10. XM_040661784.2 → XP_040517718.1  peripheral plasma membrane protein CASK isoform X9

    UniProtKB/TrEMBL
    A0A8V0X9W6
    Conserved Domains (6) summary
    smart00569
    Location:342 → 395
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:587 → 648
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:482 → 562
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:709 → 882
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:400 → 450
    L27; L27 domain

  11. XM_040661786.2 → XP_040517720.1  peripheral plasma membrane protein CASK isoform X11

    UniProtKB/TrEMBL
    A0A8V0X9W6
    Conserved Domains (6) summary
    smart00569
    Location:342 → 395
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12081
    Location:575 → 636
    SH3_CASK; Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase
    cd00992
    Location:482 → 562
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd14094
    Location:8 → 307
    STKc_CASK; Catalytic domain of the Serine/Threonine Kinase, Calcium/calmodulin-dependent serine protein kinase
    pfam00625
    Location:692 → 865
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:400 → 450
    L27; L27 domain

  12. XM_040661787.1 → XP_040517721.1  peripheral plasma membrane protein CASK isoform X12

    Conserved Domains (6) summary
    smart00569
    Location:163 → 216
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12035
    Location:431 → 492
    SH3_MPP1-like; Src Homology 3 domain of Membrane Protein, Palmitoylated 1 (or MAGUK p55 subfamily member 1)-like proteins
    cd00992
    Location:303 → 383
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:553 → 726
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:221 → 271
    L27; L27 domain
    cl21453
    Location:1 → 122
    PKc_like; Protein Kinases, catalytic domain

  13. XM_046909836.1 → XP_046765792.1  peripheral plasma membrane protein CASK isoform X13

  14. XM_040661788.2 → XP_040517722.1  peripheral plasma membrane protein CASK isoform X13

    Conserved Domains (3) summary
    cd12035
    Location:179 → 240
    SH3_MPP1-like; Src Homology 3 domain of Membrane Protein, Palmitoylated 1 (or MAGUK p55 subfamily member 1)-like proteins
    cd00992
    Location:51 → 131
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:301 → 474
    Guanylate_kin; Guanylate kinase
Nucleotide Protein
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