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nsl1 - non-specific lethal 1

Enables chromatin binding activity and histone acetyltransferase binding activity. Involved in several processes, including germ-line stem cell population maintenance; germarium-derived female germ-line cyst formation; and larval somatic muscle development. Located in cytoplasm; nucleus; and polytene chromosome interband. Part of NSL complex. Is expressed in several structures, including adult central complex; brain; fat body; follicle cell; and germline cell. Used to study Koolen de Vries syndrome and intellectual disability. Human ortholog(s) of this gene implicated in Koolen de Vries syndrome. Orthologous to several human genes including KANSL1 (KAT8 regulatory NSL complex subunit 1). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa