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SCUBE3 signal peptide, CUB domain and EGF like domain containing 3 [ Gallus gallus (chicken) ]

Gene ID: 419896, updated on 17-Aug-2024

Summary

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Symbol
SCUBE3provided by CGNC
Full Name
signal peptide, CUB domain and EGF like domain containing 3provided by CGNC
Primary source
CGNC:1927
See related
Ensembl:ENSGALG00010025917
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See SCUBE3 in Genome Data Viewer
Location:
chromosome: 26
Exon count:
25
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 26 NC_052557.1 (4175654..4217776, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 26 NC_052598.1 (4143464..4185573, complement)

Chromosome 26 - NC_052557.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124417412 Neighboring gene zinc finger protein 76 Neighboring gene ribosomal protein L10a Neighboring gene t-complex 11 Neighboring gene ankyrin repeat and sterile alpha motif domain containing 1A Neighboring gene TATA-box binding protein associated factor 11

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
signal peptide, CUB and EGF-like domain-containing protein 3
Names
signal peptide, CUB domain, EGF-like 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052557.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    4175654..4217776 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040653022.2 → XP_040508956.1  signal peptide, CUB and EGF-like domain-containing protein 3 isoform X5

    UniProtKB/TrEMBL
    A0A8V1A707
    Related
    ENSGALP00010039007.1, ENSGALT00010063194.1
    Conserved Domains (4) summary
    smart00179
    Location:53 → 93
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:801 → 912
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam07645
    Location:12 → 51
    EGF_CA; Calcium-binding EGF domain
    cl00057
    Location:312 → 348
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

  2. XM_040653023.2 → XP_040508957.1  signal peptide, CUB and EGF-like domain-containing protein 3 isoform X7

    UniProtKB/TrEMBL
    A0A8V1A701
    Related
    ENSGALP00010039002.1, ENSGALT00010063185.1
    Conserved Domains (4) summary
    smart00179
    Location:70 → 110
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:789 → 900
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam07645
    Location:29 → 68
    EGF_CA; Calcium-binding EGF domain
    cl00057
    Location:313 → 349
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

  3. XM_418021.8 → XP_418021.3  signal peptide, CUB and EGF-like domain-containing protein 3 isoform X6

    Conserved Domains (6) summary
    smart00179
    Location:70 → 110
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:796 → 907
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam07699
    Location:744 → 791
    Ephrin_rec_like; Putative ephrin-receptor like
    pfam12947
    Location:33 → 68
    EGF_3; EGF domain
    pfam14670
    Location:240 → 275
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00057
    Location:313 → 349
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

  4. XM_015299005.4 → XP_015154491.1  signal peptide, CUB and EGF-like domain-containing protein 3 isoform X4

    Conserved Domains (6) summary
    smart00179
    Location:70 → 110
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:802 → 913
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam07699
    Location:750 → 797
    Ephrin_rec_like; Putative ephrin-receptor like
    pfam12947
    Location:33 → 68
    EGF_3; EGF domain
    pfam14670
    Location:240 → 275
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00057
    Location:313 → 349
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

  5. XM_015299004.4 → XP_015154490.1  signal peptide, CUB and EGF-like domain-containing protein 3 isoform X3

    Conserved Domains (6) summary
    smart00179
    Location:70 → 110
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:805 → 916
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam07699
    Location:753 → 800
    Ephrin_rec_like; Putative ephrin-receptor like
    pfam12947
    Location:33 → 68
    EGF_3; EGF domain
    pfam14670
    Location:256 → 291
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00057
    Location:329 → 365
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

  6. XM_015299003.4 → XP_015154489.1  signal peptide, CUB and EGF-like domain-containing protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A8V1AC12
    Related
    ENSGALP00010038999.1, ENSGALT00010063181.1
    Conserved Domains (6) summary
    smart00179
    Location:70 → 110
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:812 → 923
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam07699
    Location:760 → 807
    Ephrin_rec_like; Putative ephrin-receptor like
    pfam12947
    Location:33 → 68
    EGF_3; EGF domain
    pfam14670
    Location:256 → 291
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00057
    Location:329 → 365
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

  7. XM_004935034.5 → XP_004935091.1  signal peptide, CUB and EGF-like domain-containing protein 3 isoform X1

    Conserved Domains (6) summary
    smart00179
    Location:70 → 110
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:818 → 929
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam07699
    Location:766 → 813
    Ephrin_rec_like; Putative ephrin-receptor like
    pfam12947
    Location:33 → 68
    EGF_3; EGF domain
    pfam14670
    Location:256 → 291
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00057
    Location:329 → 365
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052598.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    4143464..4185573 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040691608.2 → XP_040547542.1  signal peptide, CUB and EGF-like domain-containing protein 3 isoform X5

    UniProtKB/TrEMBL
    A0A8V1A707
    Conserved Domains (4) summary
    smart00179
    Location:53 → 93
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:801 → 912
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam07645
    Location:12 → 51
    EGF_CA; Calcium-binding EGF domain
    cl00057
    Location:312 → 348
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

  2. XM_040691610.2 → XP_040547544.1  signal peptide, CUB and EGF-like domain-containing protein 3 isoform X7

    UniProtKB/TrEMBL
    A0A8V1A701
    Conserved Domains (4) summary
    smart00179
    Location:70 → 110
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:789 → 900
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam07645
    Location:29 → 68
    EGF_CA; Calcium-binding EGF domain
    cl00057
    Location:313 → 349
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

  3. XM_040691609.2 → XP_040547543.1  signal peptide, CUB and EGF-like domain-containing protein 3 isoform X6

    Conserved Domains (6) summary
    smart00179
    Location:70 → 110
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:796 → 907
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam07699
    Location:744 → 791
    Ephrin_rec_like; Putative ephrin-receptor like
    pfam12947
    Location:33 → 68
    EGF_3; EGF domain
    pfam14670
    Location:240 → 275
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00057
    Location:313 → 349
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

  4. XM_040691606.2 → XP_040547540.1  signal peptide, CUB and EGF-like domain-containing protein 3 isoform X4

    Conserved Domains (6) summary
    smart00179
    Location:70 → 110
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:802 → 913
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam07699
    Location:750 → 797
    Ephrin_rec_like; Putative ephrin-receptor like
    pfam12947
    Location:33 → 68
    EGF_3; EGF domain
    pfam14670
    Location:240 → 275
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00057
    Location:313 → 349
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

  5. XM_040691605.2 → XP_040547539.1  signal peptide, CUB and EGF-like domain-containing protein 3 isoform X3

    Conserved Domains (6) summary
    smart00179
    Location:70 → 110
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:805 → 916
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam07699
    Location:753 → 800
    Ephrin_rec_like; Putative ephrin-receptor like
    pfam12947
    Location:33 → 68
    EGF_3; EGF domain
    pfam14670
    Location:256 → 291
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00057
    Location:329 → 365
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

  6. XM_040691604.2 → XP_040547538.1  signal peptide, CUB and EGF-like domain-containing protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A8V1AC12
    Conserved Domains (6) summary
    smart00179
    Location:70 → 110
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:812 → 923
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam07699
    Location:760 → 807
    Ephrin_rec_like; Putative ephrin-receptor like
    pfam12947
    Location:33 → 68
    EGF_3; EGF domain
    pfam14670
    Location:256 → 291
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00057
    Location:329 → 365
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

  7. XM_040691603.2 → XP_040547537.1  signal peptide, CUB and EGF-like domain-containing protein 3 isoform X1

    Conserved Domains (6) summary
    smart00179
    Location:70 → 110
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:818 → 929
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam07699
    Location:766 → 813
    Ephrin_rec_like; Putative ephrin-receptor like
    pfam12947
    Location:33 → 68
    EGF_3; EGF domain
    pfam14670
    Location:256 → 291
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00057
    Location:329 → 365
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
Nucleotide Protein Strain
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