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PLEKHF2 pleckstrin homology and FYVE domain containing 2 [ Gallus gallus (chicken) ]

Gene ID: 420234, updated on 3-Dec-2024

Summary

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Symbol
PLEKHF2provided by CGNC
Full Name
pleckstrin homology and FYVE domain containing 2provided by CGNC
Primary source
CGNC:11937
See related
Ensembl:ENSGALG00010012760
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See PLEKHF2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
8
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (126038095..126054883)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (126223606..126240409)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121109653 Neighboring gene NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 Neighboring gene C8orf37 homolog Neighboring gene uncharacterized LOC124417764 Neighboring gene transfer RNA serine (anticodon AGA)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pleckstrin homology domain-containing family F member 2
Names
PH domain-containing family F member 2
pleckstrin homology domain containing, family F (with FYVE domain) member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001030947.2 → NP_001026118.2  pleckstrin homology domain-containing family F member 2

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000044
    UniProtKB/Swiss-Prot
    Q5ZLY5
    UniProtKB/TrEMBL
    A0A1D5P7L9
    Related
    ENSGALP00010017758.1, ENSGALT00010030613.1
    Conserved Domains (2) summary
    cd01218
    Location:7 → 129
    PH_Phafin2-like; Phafin2 (also called EAPF, FLJ13187, ZFYVE18 or PLEKHF2) Pleckstrin Homology (PH) domain
    cd15755
    Location:148 → 211
    FYVE_PKHF2; FYVE domain found in protein containing both PH and FYVE domains 2 (phafin-2) and similar proteins

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    126038095..126054883
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040678622.2 → XP_040534556.1  pleckstrin homology domain-containing family F member 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5ZLY5
    UniProtKB/TrEMBL
    A0A1D5P7L9
    Related
    ENSGALP00010017747.1, ENSGALT00010030591.1
    Conserved Domains (2) summary
    cd01218
    Location:7 → 129
    PH_Phafin2-like; Phafin2 (also called EAPF, FLJ13187, ZFYVE18 or PLEKHF2) Pleckstrin Homology (PH) domain
    cd15755
    Location:148 → 211
    FYVE_PKHF2; FYVE domain found in protein containing both PH and FYVE domains 2 (phafin-2) and similar proteins

  2. XM_015282927.4 → XP_015138413.1  pleckstrin homology domain-containing family F member 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5ZLY5
    UniProtKB/TrEMBL
    A0A1D5P7L9
    Related
    ENSGALP00010017752.1, ENSGALT00010030598.1
    Conserved Domains (2) summary
    cd01218
    Location:7 → 129
    PH_Phafin2-like; Phafin2 (also called EAPF, FLJ13187, ZFYVE18 or PLEKHF2) Pleckstrin Homology (PH) domain
    cd15755
    Location:148 → 211
    FYVE_PKHF2; FYVE domain found in protein containing both PH and FYVE domains 2 (phafin-2) and similar proteins

  3. XM_015282926.4 → XP_015138412.1  pleckstrin homology domain-containing family F member 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5ZLY5
    UniProtKB/TrEMBL
    A0A1D5P7L9
    Related
    ENSGALP00010017755.1, ENSGALT00010030607.1
    Conserved Domains (2) summary
    cd01218
    Location:7 → 129
    PH_Phafin2-like; Phafin2 (also called EAPF, FLJ13187, ZFYVE18 or PLEKHF2) Pleckstrin Homology (PH) domain
    cd15755
    Location:148 → 211
    FYVE_PKHF2; FYVE domain found in protein containing both PH and FYVE domains 2 (phafin-2) and similar proteins

  4. XM_046920510.1 → XP_046776466.1  pleckstrin homology domain-containing family F member 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5ZLY5
    UniProtKB/TrEMBL
    A0A1D5P7L9

  5. XM_025147111.2 → XP_025002879.1  pleckstrin homology domain-containing family F member 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5ZLY5
    UniProtKB/TrEMBL
    A0A1D5P7L9
    Related
    ENSGALP00010017735.1, ENSGALT00010030565.1
    Conserved Domains (2) summary
    cd01218
    Location:7 → 129
    PH_Phafin2-like; Phafin2 (also called EAPF, FLJ13187, ZFYVE18 or PLEKHF2) Pleckstrin Homology (PH) domain
    cd15755
    Location:148 → 211
    FYVE_PKHF2; FYVE domain found in protein containing both PH and FYVE domains 2 (phafin-2) and similar proteins

  6. XM_046920509.1 → XP_046776465.1  pleckstrin homology domain-containing family F member 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5ZLY5
    UniProtKB/TrEMBL
    A0A1D5P7L9

  7. XM_046920506.1 → XP_046776462.1  pleckstrin homology domain-containing family F member 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5ZLY5
    UniProtKB/TrEMBL
    A0A1D5P7L9
    Related
    ENSGALP00010017745.1, ENSGALT00010030587.1

  8. XM_040678623.2 → XP_040534557.1  pleckstrin homology domain-containing family F member 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5ZLY5
    UniProtKB/TrEMBL
    A0A1D5P7L9
    Related
    ENSGALP00010017741.1, ENSGALT00010030580.1
    Conserved Domains (2) summary
    cd01218
    Location:7 → 129
    PH_Phafin2-like; Phafin2 (also called EAPF, FLJ13187, ZFYVE18 or PLEKHF2) Pleckstrin Homology (PH) domain
    cd15755
    Location:148 → 211
    FYVE_PKHF2; FYVE domain found in protein containing both PH and FYVE domains 2 (phafin-2) and similar proteins

  9. XM_015282928.4 → XP_015138414.1  pleckstrin homology domain-containing family F member 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5ZLY5
    UniProtKB/TrEMBL
    A0A1D5P7L9
    Conserved Domains (2) summary
    cd01218
    Location:7 → 129
    PH_Phafin2-like; Phafin2 (also called EAPF, FLJ13187, ZFYVE18 or PLEKHF2) Pleckstrin Homology (PH) domain
    cd15755
    Location:148 → 211
    FYVE_PKHF2; FYVE domain found in protein containing both PH and FYVE domains 2 (phafin-2) and similar proteins

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    126223606..126240409
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046910713.1 → XP_046766669.1  pleckstrin homology domain-containing family F member 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5ZLY5
    UniProtKB/TrEMBL
    A0A1D5P7L9

  2. XM_046910711.1 → XP_046766667.1  pleckstrin homology domain-containing family F member 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5ZLY5
    UniProtKB/TrEMBL
    A0A1D5P7L9

  3. XM_046910712.1 → XP_046766668.1  pleckstrin homology domain-containing family F member 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5ZLY5
    UniProtKB/TrEMBL
    A0A1D5P7L9

  4. XM_046910719.1 → XP_046766675.1  pleckstrin homology domain-containing family F member 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5ZLY5
    UniProtKB/TrEMBL
    A0A1D5P7L9

  5. XM_046910714.1 → XP_046766670.1  pleckstrin homology domain-containing family F member 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5ZLY5
    UniProtKB/TrEMBL
    A0A1D5P7L9

  6. XM_046910718.1 → XP_046766674.1  pleckstrin homology domain-containing family F member 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5ZLY5
    UniProtKB/TrEMBL
    A0A1D5P7L9

  7. XM_046910717.1 → XP_046766673.1  pleckstrin homology domain-containing family F member 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5ZLY5
    UniProtKB/TrEMBL
    A0A1D5P7L9

  8. XM_046910715.1 → XP_046766671.1  pleckstrin homology domain-containing family F member 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5ZLY5
    UniProtKB/TrEMBL
    A0A1D5P7L9

  9. XM_046910716.1 → XP_046766672.1  pleckstrin homology domain-containing family F member 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5ZLY5
    UniProtKB/TrEMBL
    A0A1D5P7L9
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5ZLY5.1 GenPept UniProtKB/Swiss-Prot:Q5ZLY5

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