CG5265 uncharacterized protein [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CG5265provided by FlyBase
Official Full Name: uncharacterized proteinprovided by FlyBase
Primary source: FLYBASE:FBgn0038486
Locus tag: Dmel_CG5265
See related: AllianceGenome:FB:FBgn0038486
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CrAT; CRAT; Dmel\CG5265
Summary: Predicted to enable carnitine O-acetyltransferase activity. Predicted to be involved in carnitine metabolic process, CoA-linked and fatty acid metabolic process. Predicted to be active in peroxisome. Is expressed in adult head and spermatozoon. Human ortholog(s) of this gene implicated in neurodegeneration with brain iron accumulation. Orthologous to human CRAT (carnitine O-acetyltransferase). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (17138999..17141168)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (12964721..12966890)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Function	Evidence Code	Pubs
enables acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables carnitine O-acetyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables carnitine O-acetyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in carnitine metabolic process, CoA-linked	IBA Inferred from Biological aspect of Ancestor more info
involved_in carnitine metabolic process, CoA-linked	ISS Inferred from Sequence or Structural Similarity more info
involved_in fatty acid beta-oxidation using acyl-CoA oxidase	ISS Inferred from Sequence or Structural Similarity more info
involved_in fatty acid metabolic process	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in mitochondrion	ISS Inferred from Sequence or Structural Similarity more info
is_active_in peroxisome	IBA Inferred from Biological aspect of Ancestor more info
located_in peroxisome	ISM Inferred from Sequence Model more info	PubMed

NP_650605.1

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The following sections contain reference sequences that belong to a specific genome build. Explain