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IGFBP3 insulin like growth factor binding protein 3 [ Gallus gallus (chicken) ]

Gene ID: 420790, updated on 17-Aug-2024

Summary

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Symbol
IGFBP3provided by CGNC
Full Name
insulin like growth factor binding protein 3provided by CGNC
Primary source
CGNC:9448
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Annotation information
Annotation category: suggests misassembly
Orthologs
human mouse all
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Genomic context

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See IGFBP3 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
4
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (54603575..54621232, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (54536467..54554126, complement)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112531745 Neighboring gene adenylate cyclase 1 Neighboring gene insulin like growth factor binding protein 1 Neighboring gene uncharacterized LOC124417788 Neighboring gene tensin 3 Neighboring gene HUS1 checkpoint clamp component

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Chicken genomics resource: sequencing and annotation of 35,407 ESTs from single and multiple tissue cDNA libraries and CAP3 assembly of a chicken gene index. Carre W, et al. Physiol Genomics, 2006 May 16. PMID 16554550
  2. A comprehensive collection of chicken cDNAs. Boardman PE, et al. Curr Biol, 2002 Nov 19. PMID 12445392
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables fibronectin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables insulin-like growth factor I binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables insulin-like growth factor II binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of insulin-like growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
insulin-like growth factor-binding protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001395957.1 → NP_001382886.1  insulin-like growth factor-binding protein 3 precursor

    Status: VALIDATED

    Source sequence(s)
    BM489002, BU299040, BU337217, BU389391, EF624351, HAEK01122495, JAENSK010000039
    UniProtKB/TrEMBL
    A6N8N6
    Conserved Domains (2) summary
    smart00121
    Location:29 → 106
    IB; Insulin growth factor-binding protein homologues
    pfam00086
    Location:204 → 276
    Thyroglobulin_1; Thyroglobulin type-1 repeat

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    54603575..54621232 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    54536467..54554126 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001101034.1: Suppressed sequence

    Description
    NM_001101034.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials