TyrR Tyramine receptor [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: TyrRprovided by FlyBase
Official Full Name: Tyramine receptorprovided by FlyBase
Primary source: FLYBASE:FBgn0038542
Locus tag: Dmel_CG7431
See related: AllianceGenome:FB:FBgn0038542
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-WO0170980.82; anon-WO0170980.83; CG7431; DmCG7431; Dmel\CG7431; DmTAR2; DrmTR; TAR2; TR; tyrR; TyrR2; TyrRII
Summary: Enables tyramine receptor activity. Involved in cellular response to amine stimulus; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway; and tyramine signaling pathway. Located in plasma membrane. Is expressed in several structures, including anterior-posterior subdivision of organism; ganglia; gut section; mushroom body; and synaptic neuropil domain. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (17750129..17763188, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (13575851..13588910, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables G protein-coupled amine receptor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables G protein-coupled receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables tyramine receptor activity	IDA Inferred from Direct Assay more info	PubMed
enables tyramine receptor activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IDA Inferred from Direct Assay more info	PubMed
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in G protein-coupled receptor signaling pathway	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in adenylate cyclase-activating adrenergic receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in cellular response to amine stimulus	IDA Inferred from Direct Assay more info	PubMed
involved_in octopamine or tyramine signaling pathway	IC Inferred by Curator more info	PubMed
involved_in positive regulation of MAPK cascade	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway	IDA Inferred from Direct Assay more info	PubMed
involved_in tyramine signaling pathway	IDA Inferred from Direct Assay more info	PubMed
involved_in tyramine signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	ISS Inferred from Sequence or Structural Similarity more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IC Inferred by Curator more info	PubMed
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed

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