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UBR2 ubiquitin protein ligase E3 component n-recognin 2 [ Gallus gallus (chicken) ]

Gene ID: 421387, updated on 17-Aug-2024

Summary

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Symbol
UBR2provided by CGNC
Full Name
ubiquitin protein ligase E3 component n-recognin 2provided by CGNC
Primary source
CGNC:7524
See related
Ensembl:ENSGALG00010018529
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See UBR2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
49
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (22673923..22725642)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (22582525..22634262)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene microRNA 1598 Neighboring gene mitochondrial ribosomal protein S10 Neighboring gene transcriptional regulating factor 1 Neighboring gene uncharacterized LOC124417881 Neighboring gene peripherin 2 Neighboring gene GLTSCR1 like Neighboring gene tubulin folding cofactor C

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ubiquitin-dependent protein catabolic process via the N-end rule pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of ubiquitin ligase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase UBR2
XP_004935399.1
XP_015139334.1
XP_040522333.1
XP_040522334.1
XP_040522335.1
XP_419446.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    22673923..22725642
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_419446.8 → XP_419446.3  E3 ubiquitin-protein ligase UBR2 isoform X2

    UniProtKB/TrEMBL
    A0A1D5P284, A0A8V0Z730
    Related
    ENSGALP00010026765.1, ENSGALT00010044843.1
    Conserved Domains (5) summary
    cd00162
    Location:1108 → 1213
    RING_Ubox; RING-H2 finger (C3H2C3-type) [structural motif]
    pfam02207
    Location:99 → 166
    zf-UBR; Putative zinc finger in N-recognin (UBR box)
    pfam02617
    Location:221 → 299
    ClpS; ATP-dependent Clp protease adaptor protein ClpS
    pfam18995
    Location:1306 → 1726
    PRT6_C; Proteolysis_6 C-terminal
    cl17238
    Location:1108 → 1222
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  2. XM_004935342.5 → XP_004935399.1  E3 ubiquitin-protein ligase UBR2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z730, E1C1D2
    Related
    ENSGALP00010026769.1, ENSGALT00010044847.1
    Conserved Domains (5) summary
    cd00162
    Location:1108 → 1213
    RING_Ubox; RING-H2 finger (C3H2C3-type) [structural motif]
    pfam02207
    Location:99 → 166
    zf-UBR; Putative zinc finger in N-recognin (UBR box)
    pfam02617
    Location:221 → 299
    ClpS; ATP-dependent Clp protease adaptor protein ClpS
    pfam18995
    Location:1306 → 1726
    PRT6_C; Proteolysis_6 C-terminal
    cl17238
    Location:1108 → 1222
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  3. XM_015283848.4 → XP_015139334.1  E3 ubiquitin-protein ligase UBR2 isoform X3

    Conserved Domains (2) summary
    pfam02207
    Location:99 → 166
    zf-UBR; Putative zinc finger in N-recognin (UBR box)
    pfam02617
    Location:221 → 299
    ClpS; ATP-dependent Clp protease adaptor protein ClpS

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    22582525..22634262
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040666400.2 → XP_040522334.1  E3 ubiquitin-protein ligase UBR2 isoform X2

    UniProtKB/TrEMBL
    A0A1D5P284, A0A8V0Z730
    Conserved Domains (5) summary
    cd00162
    Location:1108 → 1213
    RING_Ubox; RING-H2 finger (C3H2C3-type) [structural motif]
    pfam02207
    Location:99 → 166
    zf-UBR; Putative zinc finger in N-recognin (UBR box)
    pfam02617
    Location:221 → 299
    ClpS; ATP-dependent Clp protease adaptor protein ClpS
    pfam18995
    Location:1306 → 1726
    PRT6_C; Proteolysis_6 C-terminal
    cl17238
    Location:1108 → 1222
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  2. XM_040666399.2 → XP_040522333.1  E3 ubiquitin-protein ligase UBR2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z730, E1C1D2
    Conserved Domains (5) summary
    cd00162
    Location:1108 → 1213
    RING_Ubox; RING-H2 finger (C3H2C3-type) [structural motif]
    pfam02207
    Location:99 → 166
    zf-UBR; Putative zinc finger in N-recognin (UBR box)
    pfam02617
    Location:221 → 299
    ClpS; ATP-dependent Clp protease adaptor protein ClpS
    pfam18995
    Location:1306 → 1726
    PRT6_C; Proteolysis_6 C-terminal
    cl17238
    Location:1108 → 1222
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  3. XM_040666401.2 → XP_040522335.1  E3 ubiquitin-protein ligase UBR2 isoform X3

    Conserved Domains (2) summary
    pfam02207
    Location:99 → 166
    zf-UBR; Putative zinc finger in N-recognin (UBR box)
    pfam02617
    Location:221 → 299
    ClpS; ATP-dependent Clp protease adaptor protein ClpS
Nucleotide Protein Strain
Heading Accession and Version

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