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ATG5 autophagy related 5 [ Gallus gallus (chicken) ]

Gene ID: 421784, updated on 3-Dec-2024

Summary

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Official Symbol
ATG5provided by CGNC
Official Full Name
autophagy related 5provided by CGNC
Primary source
CGNC:11461
See related
Ensembl:ENSGALG00010013247
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
APG5L
Orthologs
human mouse all
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Genomic context

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See ATG5 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
17
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (67937240..68009125)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (67718832..67790798)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene absent in melanoma 1 Neighboring gene uncharacterized LOC107053080 Neighboring gene uncharacterized LOC107053079 Neighboring gene uncharacterized LOC121110218 Neighboring gene uncharacterized LOC121110217 Neighboring gene PR/SET domain 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Knockout of Atg5 inhibits proliferation and promotes apoptosis of DF-1 cells. Liao Z, et al. In Vitro Cell Dev Biol Anim, 2019 May. PMID 31025250
  2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. All these findings indicated that Atg5 plays an important role in the proliferation of DF-1 cells.
    Title: Knockout of Atg5 inhibits proliferation and promotes apoptosis of DF-1 cells.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in C-terminal protein lipidation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in autophagosome assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in autophagy of mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to nitrogen starvation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nucleophagy IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Atg12-Atg5-Atg16 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in phagophore assembly site membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
autophagy protein 5
Names
ATG5 autophagy related 5 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001006409.2 → NP_001006409.1  autophagy protein 5

    See identical proteins and their annotated locations for NP_001006409.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000065
    UniProtKB/TrEMBL
    A0A1D5PK91, A0A8V0YR58, Q5ZHW2
    Related
    ENSGALP00010018651.1, ENSGALT00010031847.1
    Conserved Domains (1) summary
    pfam04106
    Location:79 → 270
    APG5; Autophagy protein Apg5

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    67937240..68009125
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046938875.1 → XP_046794831.1  autophagy protein 5 isoform X6

    UniProtKB/TrEMBL
    A0A8V0YR58

  2. XM_046938874.1 → XP_046794830.1  autophagy protein 5 isoform X4

    UniProtKB/TrEMBL
    A0A8V0YR53, F7AY48

  3. XM_046938873.1 → XP_046794829.1  autophagy protein 5 isoform X2

    UniProtKB/TrEMBL
    A0A1D5PK91, A0A8V0YR58, Q5ZHW2

  4. XM_046938876.1 → XP_046794832.1  autophagy protein 5 isoform X9

    UniProtKB/TrEMBL
    A0A8V0YR53

  5. XM_040697155.2 → XP_040553089.1  autophagy protein 5 isoform X6

    UniProtKB/TrEMBL
    A0A8V0YR58

  6. XM_015284519.4 → XP_015140005.1  autophagy protein 5 isoform X4

    UniProtKB/TrEMBL
    A0A8V0YR53, F7AY48
    Related
    ENSGALP00010018650.1, ENSGALT00010031846.1
    Conserved Domains (1) summary
    pfam04106
    Location:79 → 244
    APG5; Autophagy protein Apg5

  7. XM_015284523.4 → XP_015140009.1  autophagy protein 5 isoform X8

    UniProtKB/TrEMBL
    A0A8V0YJA5, A0A8V0YR58
    Related
    ENSGALP00010018644.1, ENSGALT00010031839.1
    Conserved Domains (1) summary
    pfam04106
    Location:79 → 225
    APG5; Autophagy protein Apg5

  8. XM_015284520.4 → XP_015140006.1  autophagy protein 5 isoform X5

    UniProtKB/TrEMBL
    A0A8V0YJA5
    Related
    ENSGALP00010018646.1, ENSGALT00010031841.1
    Conserved Domains (1) summary
    pfam04106
    Location:79 → 225
    APG5; Autophagy protein Apg5

  9. XM_015284521.4 → XP_015140007.1  autophagy protein 5 isoform X7

    UniProtKB/TrEMBL
    A0A8V0YCX7
    Conserved Domains (1) summary
    pfam04106
    Location:79 → 235
    APG5; Autophagy protein Apg5

  10. XM_015284518.4 → XP_015140004.1  autophagy protein 5 isoform X3

    UniProtKB/TrEMBL
    A0A8V0YJA5
    Conserved Domains (1) summary
    pfam04106
    Location:72 → 218
    APG5; Autophagy protein Apg5

  11. XM_015284516.4 → XP_015140002.1  autophagy protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0YJA5
    Conserved Domains (1) summary
    pfam04106
    Location:79 → 225
    APG5; Autophagy protein Apg5

  12. XM_040697158.2 → XP_040553092.1  autophagy protein 5 isoform X13

    UniProtKB/TrEMBL
    A0A8V0YCX7

  13. XM_040697156.2 → XP_040553090.1  autophagy protein 5 isoform X11

    UniProtKB/TrEMBL
    A0A8V0YCX7

  14. XM_040697157.2 → XP_040553091.1  autophagy protein 5 isoform X10

  15. XM_046938877.1 → XP_046794833.1  autophagy protein 5 isoform X12

RNA

  1. XR_006938655.1 RNA Sequence

  2. XR_006938656.1 RNA Sequence

  3. XR_003074222.3 RNA Sequence

  4. XR_001466036.4 RNA Sequence

  5. XR_001466037.4 RNA Sequence

  6. XR_003074223.3 RNA Sequence

  7. XR_003074224.3 RNA Sequence

  8. XR_005858085.2 RNA Sequence

  9. XR_003074225.3 RNA Sequence

  10. XR_005858086.2 RNA Sequence

  11. XR_003074226.3 RNA Sequence

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    67718832..67790798
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046914040.1 → XP_046769996.1  autophagy protein 5 isoform X6

    UniProtKB/TrEMBL
    A0A8V0YR58

  2. XM_046914037.1 → XP_046769993.1  autophagy protein 5 isoform X4

    UniProtKB/TrEMBL
    A0A8V0YR53, F7AY48

  3. XM_046914034.1 → XP_046769990.1  autophagy protein 5 isoform X2

    UniProtKB/TrEMBL
    A0A1D5PK91, A0A8V0YR58, Q5ZHW2

  4. XM_046914043.1 → XP_046769999.1  autophagy protein 5 isoform X9

    UniProtKB/TrEMBL
    A0A8V0YR53

  5. XM_046914039.1 → XP_046769995.1  autophagy protein 5 isoform X6

    UniProtKB/TrEMBL
    A0A8V0YR58

  6. XM_046914036.1 → XP_046769992.1  autophagy protein 5 isoform X4

    UniProtKB/TrEMBL
    A0A8V0YR53, F7AY48

  7. XM_046914042.1 → XP_046769998.1  autophagy protein 5 isoform X8

    UniProtKB/TrEMBL
    A0A8V0YJA5, A0A8V0YR58

  8. XM_046914038.1 → XP_046769994.1  autophagy protein 5 isoform X5

    UniProtKB/TrEMBL
    A0A8V0YJA5

  9. XM_046914041.1 → XP_046769997.1  autophagy protein 5 isoform X7

    UniProtKB/TrEMBL
    A0A8V0YCX7

  10. XM_046914035.1 → XP_046769991.1  autophagy protein 5 isoform X3

    UniProtKB/TrEMBL
    A0A8V0YJA5

  11. XM_046914033.1 → XP_046769989.1  autophagy protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0YJA5

  12. XM_046914044.1 → XP_046770000.1  autophagy protein 5 isoform X10

RNA

  1. XR_006933963.1 RNA Sequence

  2. XR_006933964.1 RNA Sequence

  3. XR_006933954.1 RNA Sequence

  4. XR_006933953.1 RNA Sequence

  5. XR_006933956.1 RNA Sequence

  6. XR_006933955.1 RNA Sequence

  7. XR_006933958.1 RNA Sequence

  8. XR_006933957.1 RNA Sequence

  9. XR_006933959.1 RNA Sequence

  10. XR_006933960.1 RNA Sequence

  11. XR_006933961.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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