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Polr1E RNA polymerase I subunit E [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42201, updated on 9-Dec-2024

Summary

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Official Symbol
Polr1Eprovided by FlyBase
Official Full Name
RNA polymerase I subunit Eprovided by FlyBase
Primary source
FLYBASE:FBgn0038601
Locus tag
Dmel_CG18600
See related
AllianceGenome:FB:FBgn0038601
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BEST:CK01205; CG18600; CK01205; Dmel\CG18600; RPA49
Summary
Predicted to enable DNA binding activity. Predicted to be involved in RNA polymerase I preinitiation complex assembly and transcription elongation by RNA polymerase I. Predicted to be part of RNA polymerase I complex. Is expressed in several structures, including antennal anlage; anterior endoderm; anterior endoderm anlage; embryonic/larval midgut primordium; and mesoderm. Orthologous to human POLR1E (RNA polymerase I subunit E). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Polr1E in Genome Data Viewer
Location:
91A2-91A2; 3-63 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (18300195..18301728, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (14125917..14127450, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene lethal (3) 05822 Neighboring gene Dynein light chain 90F Neighboring gene uncharacterized protein Neighboring gene Protein Kinase D

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. dtctex-1, the Drosophila melanogaster homolog of a putative murine t-complex distorter encoding a dynein light chain, is required for production of functional sperm. Caggese C, et al. Mol Genet Genomics, 2001 May. PMID 11405626
  2. The Drosophila tctex-1 light chain is dispensable for essential cytoplasmic dynein functions but is required during spermatid differentiation. Li MG, et al. Mol Biol Cell, 2004 Jul. PMID 15090621, Free PMC Article
  3. PNUTS/PP1 regulates RNAPII-mediated gene expression and is necessary for developmental growth. Ciurciu A, et al. PLoS Genet, 2013 Oct. PMID 24204300, Free PMC Article
  4. In silico identification of Drosophila melanogaster genes encoding RNA polymerase subunits. Marygold SJ, et al. MicroPubl Biol, 2020 Oct 20. PMID 33274328, Free PMC Article
  5. Functional genomics identifies TOR-regulated genes that control growth and division. Guertin DA, et al. Curr Biol, 2006 May 23. PMID 16713952

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in RNA polymerase I preinitiation complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transcription elongation by RNA polymerase I IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of RNA polymerase I complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
RNA polymerase I subunit E
Names
CG18600-PA
Polr1E-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    18300195..18301728 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142451.3 → NP_650708.1  RNA polymerase I subunit E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650708.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VE94
    Related
    FBpp0083015
    Conserved Domains (1) summary
    pfam06870
    Location:33 → 379
    RNA_pol_I_A49; A49-like RNA polymerase I associated factor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VE94 Q9VE94

Gene LinkOut

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