vib vibrator [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: vibprovided by FlyBase
Official Full Name: vibratorprovided by FlyBase
Primary source: FLYBASE:FBgn0267975
Locus tag: Dmel_CG5269
See related: AllianceGenome:FB:FBgn0267975
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 0450/02; 1104/16; anon-WO0142479.3; anon-WO0172774.12; anon-WO0172774.16; anon-WO0172774.28; CG5269; Dm-PITPalpha; Dmel\CG5269; gio; Gio; giotto; l(3)j4A3; l(3)j5A6; l(3)j7A3; l(3)j7C8; l(3)S045002; l(3)S045002c; l(3)S110416; PITP; PITP-DM; Vib
Summary: Predicted to enable phospholipid binding activity and phospholipid transporter activity. Involved in cytoskeleton-dependent cytokinesis; meiotic spindle organization; and spermatocyte division. Located in several cellular components, including Nebenkern; cleavage furrow; and spindle envelope. Is expressed in several structures, including adult head; adult heart; embryonic/larval fat body; gut section; and spermatocyte. Orthologous to human PITPNA (phosphatidylinositol transfer protein alpha) and PITPNB (phosphatidylinositol transfer protein beta). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (19215434..19226651, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (15041156..15052373, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables phosphatidylcholine binding	IBA Inferred from Biological aspect of Ancestor more info
enables phosphatidylcholine transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables phosphatidylinositol binding	IBA Inferred from Biological aspect of Ancestor more info
enables phosphatidylinositol transfer activity	IBA Inferred from Biological aspect of Ancestor more info
enables phospholipid transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in actomyosin contractile ring contraction	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cleavage furrow ingression	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in male meiosis cytokinesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in meiosis I cytokinesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in meiosis II cytokinesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in meiotic cytokinesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in meiotic spindle organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in phospholipid transport	IEA Inferred from Electronic Annotation more info
involved_in spermatocyte division	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in spermatogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	IDA Inferred from Direct Assay more info	PubMed
located_in Nebenkern	IDA Inferred from Direct Assay more info	PubMed
located_in cleavage furrow	IDA Inferred from Direct Assay more info	PubMed
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in nuclear membrane	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in spindle envelope	IDA Inferred from Direct Assay more info	PubMed

Names: CG5269-PA; CG5269-PB; CG5269-PC; PITP; giotto; lethal (3) S045002c; lethal (3) S110416; lethal (3) j5A6; vib-PA; vib-PB; vib-PC

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The following sections contain reference sequences that belong to a specific genome build. Explain