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PLEKHH1 pleckstrin homology, MyTH4 and FERM domain containing H1 [ Gallus gallus (chicken) ]

Gene ID: 423270, updated on 3-Dec-2024

Summary

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Symbol
PLEKHH1provided by CGNC
Full Name
pleckstrin homology, MyTH4 and FERM domain containing H1provided by CGNC
Primary source
CGNC:7235
See related
Ensembl:ENSGALG00010019875
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See PLEKHH1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
33
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (28316469..28371196)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (28276448..28331168)

Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 229B Neighboring gene uncharacterized LOC101749472 Neighboring gene uncharacterized LOC112532518 Neighboring gene uncharacterized LOC124418038 Neighboring gene phosphatidylinositol glycan anchor biosynthesis class H Neighboring gene arginase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pleckstrin homology domain-containing family H member 1
Names
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    28316469..28371196
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025151140.3 → XP_025006908.2  pleckstrin homology domain-containing family H member 1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZIC6
    Conserved Domains (7) summary
    smart00139
    Location:912 → 1066
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00233
    Location:769 → 871
    PH; Pleckstrin homology domain
    smart00295
    Location:1079 → 1310
    B41; Band 4.1 homologues
    cd13206
    Location:1306 → 1408
    FERM_C-lobe_PLEKHH1_PLEKHH2; FERM domain C-lobe of Pleckstrin homology domain-containing family H
    cd13282
    Location:662 → 757
    PH1_PLEKHH1_PLEKHH2; Pleckstrin homology (PH) domain containing, family H (with MyTH4 domain) members 1 and 2 (PLEKHH1) PH domain, repeat 1
    TIGR02168
    Location:31 → 169
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd17178
    Location:1076 → 1182
    FERM_F1_PLEKHH1; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in pleckstrin homology domain-containing family H member 1 (PLEKHH1)

  2. XM_040701535.2 → XP_040557469.1  pleckstrin homology domain-containing family H member 1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZIC6
    Conserved Domains (7) summary
    smart00139
    Location:912 → 1066
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00233
    Location:769 → 871
    PH; Pleckstrin homology domain
    smart00295
    Location:1079 → 1310
    B41; Band 4.1 homologues
    cd13206
    Location:1306 → 1408
    FERM_C-lobe_PLEKHH1_PLEKHH2; FERM domain C-lobe of Pleckstrin homology domain-containing family H
    cd13282
    Location:662 → 757
    PH1_PLEKHH1_PLEKHH2; Pleckstrin homology (PH) domain containing, family H (with MyTH4 domain) members 1 and 2 (PLEKHH1) PH domain, repeat 1
    TIGR02168
    Location:31 → 169
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd17178
    Location:1076 → 1182
    FERM_F1_PLEKHH1; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in pleckstrin homology domain-containing family H member 1 (PLEKHH1)

  3. XM_040701536.2 → XP_040557470.1  pleckstrin homology domain-containing family H member 1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZIC6
    Conserved Domains (7) summary
    smart00139
    Location:912 → 1066
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00233
    Location:769 → 871
    PH; Pleckstrin homology domain
    smart00295
    Location:1079 → 1310
    B41; Band 4.1 homologues
    cd13206
    Location:1306 → 1408
    FERM_C-lobe_PLEKHH1_PLEKHH2; FERM domain C-lobe of Pleckstrin homology domain-containing family H
    cd13282
    Location:662 → 757
    PH1_PLEKHH1_PLEKHH2; Pleckstrin homology (PH) domain containing, family H (with MyTH4 domain) members 1 and 2 (PLEKHH1) PH domain, repeat 1
    TIGR02168
    Location:31 → 169
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd17178
    Location:1076 → 1182
    FERM_F1_PLEKHH1; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in pleckstrin homology domain-containing family H member 1 (PLEKHH1)

  4. XM_004941713.5 → XP_004941770.2  pleckstrin homology domain-containing family H member 1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZIC6
    Conserved Domains (7) summary
    smart00139
    Location:912 → 1066
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00233
    Location:769 → 871
    PH; Pleckstrin homology domain
    smart00295
    Location:1079 → 1310
    B41; Band 4.1 homologues
    cd13206
    Location:1306 → 1408
    FERM_C-lobe_PLEKHH1_PLEKHH2; FERM domain C-lobe of Pleckstrin homology domain-containing family H
    cd13282
    Location:662 → 757
    PH1_PLEKHH1_PLEKHH2; Pleckstrin homology (PH) domain containing, family H (with MyTH4 domain) members 1 and 2 (PLEKHH1) PH domain, repeat 1
    TIGR02168
    Location:31 → 169
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd17178
    Location:1076 → 1182
    FERM_F1_PLEKHH1; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in pleckstrin homology domain-containing family H member 1 (PLEKHH1)

  5. XM_040701538.2 → XP_040557472.1  pleckstrin homology domain-containing family H member 1 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZCE8, A0A8V0ZIC6
    Related
    ENSGALP00010028358.1, ENSGALT00010048045.1
    Conserved Domains (7) summary
    smart00139
    Location:905 → 1059
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00233
    Location:762 → 864
    PH; Pleckstrin homology domain
    smart00295
    Location:1072 → 1303
    B41; Band 4.1 homologues
    cd13206
    Location:1299 → 1401
    FERM_C-lobe_PLEKHH1_PLEKHH2; FERM domain C-lobe of Pleckstrin homology domain-containing family H
    cd13282
    Location:655 → 750
    PH1_PLEKHH1_PLEKHH2; Pleckstrin homology (PH) domain containing, family H (with MyTH4 domain) members 1 and 2 (PLEKHH1) PH domain, repeat 1
    TIGR02168
    Location:31 → 169
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd17178
    Location:1069 → 1175
    FERM_F1_PLEKHH1; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in pleckstrin homology domain-containing family H member 1 (PLEKHH1)

  6. XM_040701539.2 → XP_040557473.1  pleckstrin homology domain-containing family H member 1 isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZBR7
    Related
    ENSGALP00010028354.1, ENSGALT00010048037.1
    Conserved Domains (7) summary
    smart00139
    Location:912 → 1066
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00233
    Location:769 → 871
    PH; Pleckstrin homology domain
    smart00295
    Location:1079 → 1310
    B41; Band 4.1 homologues
    cd13282
    Location:662 → 757
    PH1_PLEKHH1_PLEKHH2; Pleckstrin homology (PH) domain containing, family H (with MyTH4 domain) members 1 and 2 (PLEKHH1) PH domain, repeat 1
    TIGR02168
    Location:31 → 169
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd17178
    Location:1076 → 1182
    FERM_F1_PLEKHH1; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in pleckstrin homology domain-containing family H member 1 (PLEKHH1)
    cl17171
    Location:1306 → 1342
    PH-like; Pleckstrin homology-like domain

  7. XM_040701537.2 → XP_040557471.1  pleckstrin homology domain-containing family H member 1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZIC6
    Conserved Domains (7) summary
    smart00139
    Location:912 → 1066
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00233
    Location:769 → 871
    PH; Pleckstrin homology domain
    smart00295
    Location:1079 → 1310
    B41; Band 4.1 homologues
    cd13206
    Location:1306 → 1408
    FERM_C-lobe_PLEKHH1_PLEKHH2; FERM domain C-lobe of Pleckstrin homology domain-containing family H
    cd13282
    Location:662 → 757
    PH1_PLEKHH1_PLEKHH2; Pleckstrin homology (PH) domain containing, family H (with MyTH4 domain) members 1 and 2 (PLEKHH1) PH domain, repeat 1
    TIGR02168
    Location:31 → 169
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd17178
    Location:1076 → 1182
    FERM_F1_PLEKHH1; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in pleckstrin homology domain-containing family H member 1 (PLEKHH1)

  8. XM_040701540.1 → XP_040557474.1  pleckstrin homology domain-containing family H member 1 isoform X4

    UniProtKB/TrEMBL
    A0A8V0ZIC6
    Related
    ENSGALP00010028346.1, ENSGALT00010048020.1
    Conserved Domains (6) summary
    smart00139
    Location:743 → 897
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00233
    Location:600 → 702
    PH; Pleckstrin homology domain
    smart00295
    Location:910 → 1141
    B41; Band 4.1 homologues
    cd13206
    Location:1137 → 1239
    FERM_C-lobe_PLEKHH1_PLEKHH2; FERM domain C-lobe of Pleckstrin homology domain-containing family H
    cd13282
    Location:493 → 588
    PH1_PLEKHH1_PLEKHH2; Pleckstrin homology (PH) domain containing, family H (with MyTH4 domain) members 1 and 2 (PLEKHH1) PH domain, repeat 1
    cd17178
    Location:907 → 1013
    FERM_F1_PLEKHH1; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in pleckstrin homology domain-containing family H member 1 (PLEKHH1)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    28276448..28331168
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040673882.2 → XP_040529816.2  pleckstrin homology domain-containing family H member 1 isoform X5

    UniProtKB/TrEMBL
    A0A8V0ZIC6

  2. XM_040673883.2 → XP_040529817.2  pleckstrin homology domain-containing family H member 1 isoform X6

    UniProtKB/TrEMBL
    A0A8V0ZIC6

  3. XM_040673884.2 → XP_040529818.2  pleckstrin homology domain-containing family H member 1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZIC6

  4. XM_040673885.2 → XP_040529819.2  pleckstrin homology domain-containing family H member 1 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZIC6

  5. XM_040673891.2 → XP_040529825.2  pleckstrin homology domain-containing family H member 1 isoform X7

    UniProtKB/TrEMBL
    A0A8V0ZBR7

  6. XM_040673887.2 → XP_040529821.1  pleckstrin homology domain-containing family H member 1 isoform X5

    UniProtKB/TrEMBL
    A0A8V0ZIC6
    Conserved Domains (7) summary
    smart00139
    Location:929 → 1083
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00233
    Location:786 → 888
    PH; Pleckstrin homology domain
    smart00295
    Location:1096 → 1327
    B41; Band 4.1 homologues
    cd13206
    Location:1323 → 1425
    FERM_C-lobe_PLEKHH1_PLEKHH2; FERM domain C-lobe of Pleckstrin homology domain-containing family H
    cd13282
    Location:679 → 774
    PH1_PLEKHH1_PLEKHH2; Pleckstrin homology (PH) domain containing, family H (with MyTH4 domain) members 1 and 2 (PLEKHH1) PH domain, repeat 1
    TIGR02168
    Location:31 → 169
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd17178
    Location:1093 → 1199
    FERM_F1_PLEKHH1; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in pleckstrin homology domain-containing family H member 1 (PLEKHH1)

  7. XM_040673888.2 → XP_040529822.1  pleckstrin homology domain-containing family H member 1 isoform X5

    UniProtKB/TrEMBL
    A0A8V0ZIC6
    Conserved Domains (7) summary
    smart00139
    Location:929 → 1083
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00233
    Location:786 → 888
    PH; Pleckstrin homology domain
    smart00295
    Location:1096 → 1327
    B41; Band 4.1 homologues
    cd13206
    Location:1323 → 1425
    FERM_C-lobe_PLEKHH1_PLEKHH2; FERM domain C-lobe of Pleckstrin homology domain-containing family H
    cd13282
    Location:679 → 774
    PH1_PLEKHH1_PLEKHH2; Pleckstrin homology (PH) domain containing, family H (with MyTH4 domain) members 1 and 2 (PLEKHH1) PH domain, repeat 1
    TIGR02168
    Location:31 → 169
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd17178
    Location:1093 → 1199
    FERM_F1_PLEKHH1; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in pleckstrin homology domain-containing family H member 1 (PLEKHH1)

  8. XM_040673886.2 → XP_040529820.1  pleckstrin homology domain-containing family H member 1 isoform X5

    UniProtKB/TrEMBL
    A0A8V0ZIC6
    Conserved Domains (7) summary
    smart00139
    Location:929 → 1083
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00233
    Location:786 → 888
    PH; Pleckstrin homology domain
    smart00295
    Location:1096 → 1327
    B41; Band 4.1 homologues
    cd13206
    Location:1323 → 1425
    FERM_C-lobe_PLEKHH1_PLEKHH2; FERM domain C-lobe of Pleckstrin homology domain-containing family H
    cd13282
    Location:679 → 774
    PH1_PLEKHH1_PLEKHH2; Pleckstrin homology (PH) domain containing, family H (with MyTH4 domain) members 1 and 2 (PLEKHH1) PH domain, repeat 1
    TIGR02168
    Location:31 → 169
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd17178
    Location:1093 → 1199
    FERM_F1_PLEKHH1; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in pleckstrin homology domain-containing family H member 1 (PLEKHH1)

  9. XM_046919647.1 → XP_046775603.1  pleckstrin homology domain-containing family H member 1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZIC6

  10. XM_040673890.2 → XP_040529824.1  pleckstrin homology domain-containing family H member 1 isoform X5

    UniProtKB/TrEMBL
    A0A8V0ZIC6
    Conserved Domains (7) summary
    smart00139
    Location:929 → 1083
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00233
    Location:786 → 888
    PH; Pleckstrin homology domain
    smart00295
    Location:1096 → 1327
    B41; Band 4.1 homologues
    cd13206
    Location:1323 → 1425
    FERM_C-lobe_PLEKHH1_PLEKHH2; FERM domain C-lobe of Pleckstrin homology domain-containing family H
    cd13282
    Location:679 → 774
    PH1_PLEKHH1_PLEKHH2; Pleckstrin homology (PH) domain containing, family H (with MyTH4 domain) members 1 and 2 (PLEKHH1) PH domain, repeat 1
    TIGR02168
    Location:31 → 169
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd17178
    Location:1093 → 1199
    FERM_F1_PLEKHH1; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in pleckstrin homology domain-containing family H member 1 (PLEKHH1)

  11. XM_040673892.1 → XP_040529826.1  pleckstrin homology domain-containing family H member 1 isoform X8

    UniProtKB/TrEMBL
    A0A8V0ZIC6
    Conserved Domains (6) summary
    smart00139
    Location:760 → 914
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00233
    Location:617 → 719
    PH; Pleckstrin homology domain
    smart00295
    Location:927 → 1158
    B41; Band 4.1 homologues
    cd13206
    Location:1154 → 1256
    FERM_C-lobe_PLEKHH1_PLEKHH2; FERM domain C-lobe of Pleckstrin homology domain-containing family H
    cd13282
    Location:510 → 605
    PH1_PLEKHH1_PLEKHH2; Pleckstrin homology (PH) domain containing, family H (with MyTH4 domain) members 1 and 2 (PLEKHH1) PH domain, repeat 1
    cd17178
    Location:924 → 1030
    FERM_F1_PLEKHH1; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in pleckstrin homology domain-containing family H member 1 (PLEKHH1)
Nucleotide Protein Strain
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