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Acsx1L Acyl-CoA synthetase X1 L [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42351, updated on 4-Jan-2025

Summary

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Official Symbol
Acsx1Lprovided by FlyBase
Official Full Name
Acyl-CoA synthetase X1 Lprovided by FlyBase
Primary source
FLYBASE:FBgn0038730
Locus tag
Dmel_CG6300
See related
AllianceGenome:FB:FBgn0038730
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG6300; Dmel\CG6300
Summary
Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in fatty-acyl-CoA biosynthetic process and long-chain fatty acid metabolic process. Is expressed in embryonic hindgut; embryonic precursor of adult hindgut; and yolk nucleus. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See Acsx1L in Genome Data Viewer
Location:
92B2-92B2; 3-67 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (19771382..19773225, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (15597104..15598947, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Glutamate-gated chloride channel subunit alpha Neighboring gene long non-coding RNA:CR43488 Neighboring gene Acyl-CoA synthetase X1 R Neighboring gene Acyl-CoA synthetase X2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A tandem duplication in Drosophila melanogaster shows enhanced expression beyond the gene copy number. Loehlin DW, et al. Genetics, 2022 Mar 3. PMID 35100388, Free PMC Article
  2. Evidence for the fixation of gene duplications by positive selection in Drosophila. Cardoso-Moreira M, et al. Genome Res, 2016 Jun. PMID 27197209, Free PMC Article
  3. Steroid Hormone Signaling Is Essential for Pheromone Production and Oenocyte Survival. Chiang YN, et al. PLoS Genet, 2016 Jun. PMID 27333054, Free PMC Article
  4. Methylmercury activates enhancer-of-split and bearded complex genes independent of the notch receptor. Rand MD, et al. Toxicol Sci, 2008 Jul. PMID 18367466
  5. The DHR96 nuclear receptor regulates xenobiotic responses in Drosophila. King-Jones K, et al. Cell Metab, 2006 Jul. PMID 16814731

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables long-chain fatty acid-CoA ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in fatty-acyl-CoA biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in long-chain fatty acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Acyl-CoA synthetase X1 L
Names
Acsx1L-PA
CG6300-PA
NP_650828.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    19771382..19773225 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142571.3 → NP_650828.1  Acyl-CoA synthetase X1 L [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650828.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VDU4
    Related
    FBpp0083209
    Conserved Domains (2) summary
    COG0318
    Location:26 → 523
    CaiC; Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]
    cl17068
    Location:47 → 522
    AFD_class_I; Adenylate forming domain, Class I superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VDU4 Q9VDU4

Gene LinkOut

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