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Acsx1R Acyl-CoA synthetase X1 R [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42352, updated on 4-Jan-2025

Summary

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Official Symbol
Acsx1Rprovided by FlyBase
Official Full Name
Acyl-CoA synthetase X1 Rprovided by FlyBase
Primary source
FLYBASE:FBgn0038731
Locus tag
Dmel_CG11659
See related
AllianceGenome:FB:FBgn0038731
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG11659; Dmel\CG11659
Summary
Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in fatty-acyl-CoA biosynthetic process and long-chain fatty acid metabolic process. Is expressed in embryonic hindgut; embryonic precursor of adult hindgut; and yolk nucleus. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See Acsx1R in Genome Data Viewer
Location:
92B2-92B2; 3-67 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (19775459..19777280, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (15601181..15603002, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Glutamate-gated chloride channel subunit alpha Neighboring gene long non-coding RNA:CR43488 Neighboring gene Acyl-CoA synthetase X1 L Neighboring gene Acyl-CoA synthetase X2 Neighboring gene Acyl-CoA synthetase X3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A tandem duplication in Drosophila melanogaster shows enhanced expression beyond the gene copy number. Loehlin DW, et al. Genetics, 2022 Mar 3. PMID 35100388, Free PMC Article
  2. The DHR96 nuclear receptor regulates xenobiotic responses in Drosophila. King-Jones K, et al. Cell Metab, 2006 Jul. PMID 16814731
  3. A Membrane Transporter Is Required for Steroid Hormone Uptake in Drosophila. Okamoto N, et al. Dev Cell, 2018 Nov 5. PMID 30293839, Free PMC Article
  4. Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome. Watkins PA, et al. J Lipid Res, 2007 Dec. PMID 17762044
  5. Cdk8 attenuates lipogenesis by inhibiting SREBP-dependent transcription in Drosophila. Li X, et al. Dis Model Mech, 2022 Nov 1. PMID 36305265, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables long-chain fatty acid-CoA ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in fatty-acyl-CoA biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in long-chain fatty acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Acyl-CoA synthetase X1 R
Names
Acsx1R-PA
CG11659-PA
NP_650829.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    19775459..19777280 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142572.2 → NP_650829.1  Acyl-CoA synthetase X1 R [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650829.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VDU3
    Related
    FBpp0083208
    Conserved Domains (2) summary
    COG0318
    Location:26 → 523
    CaiC; Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]
    cl17068
    Location:47 → 522
    AFD_class_I; Adenylate forming domain, Class I superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VDU3 Q9VDU3

Gene LinkOut

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