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PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A [ Gallus gallus (chicken) ]

Gene ID: 423525, updated on 3-Dec-2024

Summary

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Symbol
PPM1Aprovided by CGNC
Full Name
protein phosphatase, Mg2+/Mn2+ dependent 1Aprovided by CGNC
Primary source
CGNC:9036
See related
Ensembl:ENSGALG00010016903
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See PPM1A in Genome Data Viewer
Location:
chromosome: 5
Exon count:
7
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (54014859..54047791, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (54003411..54036358, complement)

Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene chromosome 5 open reading frame, human C14orf39 Neighboring gene SIX homeobox 6 Neighboring gene uncharacterized LOC107053579 Neighboring gene dehydrogenase/reductase 7 Neighboring gene pecanex 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables manganese ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein phosphatase 1A
XP_015143400.1
XP_015143401.1
XP_015143402.1
XP_040529742.1
XP_040529743.1
XP_040529744.1
XP_040529745.1
XP_040529746.1
XP_040557561.1
XP_040557563.1
XP_046775415.1
XP_046775416.1
XP_046798422.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    54014859..54047791 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040701629.2 → XP_040557563.1  protein phosphatase 1A isoform X2

    UniProtKB/TrEMBL
    A0A8V0Z031, E1BVM8
    Conserved Domains (2) summary
    cd00143
    Location:23 → 291
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
    pfam07830
    Location:285 → 363
    PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

  2. XM_040701627.2 → XP_040557561.1  protein phosphatase 1A isoform X1

    UniProtKB/TrEMBL
    A0A8V0YY86, A0A8V0Z031
    Related
    ENSGALP00010023751.1, ENSGALT00010040787.1
    Conserved Domains (2) summary
    cd00143
    Location:23 → 291
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
    pfam07830
    Location:285 → 363
    PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

  3. XM_015287916.4 → XP_015143402.1  protein phosphatase 1A isoform X3

    UniProtKB/TrEMBL
    A0A8V0Z031
    Conserved Domains (2) summary
    cd00143
    Location:23 → 291
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
    cl29762
    Location:285 → 318
    PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

  4. XM_015287915.4 → XP_015143401.1  protein phosphatase 1A isoform X2

    UniProtKB/TrEMBL
    A0A8V0Z031, E1BVM8
    Related
    ENSGALP00010023753.1, ENSGALT00010040789.1
    Conserved Domains (2) summary
    cd00143
    Location:23 → 291
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
    pfam07830
    Location:285 → 363
    PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

  5. XM_015287914.4 → XP_015143400.1  protein phosphatase 1A isoform X1

    UniProtKB/TrEMBL
    A0A8V0YY86, A0A8V0Z031
    Conserved Domains (2) summary
    cd00143
    Location:23 → 291
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
    pfam07830
    Location:285 → 363
    PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

  6. XM_046942466.1 → XP_046798422.1  protein phosphatase 1A isoform X1

    UniProtKB/TrEMBL
    A0A8V0YY86, A0A8V0Z031

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    54003411..54036358 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040673811.2 → XP_040529745.1  protein phosphatase 1A isoform X2

    UniProtKB/TrEMBL
    A0A8V0Z031, E1BVM8
    Conserved Domains (2) summary
    cd00143
    Location:23 → 291
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
    pfam07830
    Location:285 → 363
    PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

  2. XM_040673809.2 → XP_040529743.1  protein phosphatase 1A isoform X1

    UniProtKB/TrEMBL
    A0A8V0YY86, A0A8V0Z031
    Conserved Domains (2) summary
    cd00143
    Location:23 → 291
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
    pfam07830
    Location:285 → 363
    PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

  3. XM_040673812.2 → XP_040529746.1  protein phosphatase 1A isoform X3

    UniProtKB/TrEMBL
    A0A8V0Z031
    Conserved Domains (2) summary
    cd00143
    Location:23 → 291
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
    cl29762
    Location:285 → 318
    PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

  4. XM_040673810.2 → XP_040529744.1  protein phosphatase 1A isoform X2

    UniProtKB/TrEMBL
    A0A8V0Z031, E1BVM8
    Conserved Domains (2) summary
    cd00143
    Location:23 → 291
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
    pfam07830
    Location:285 → 363
    PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

  5. XM_040673808.2 → XP_040529742.1  protein phosphatase 1A isoform X1

    UniProtKB/TrEMBL
    A0A8V0YY86, A0A8V0Z031
    Conserved Domains (2) summary
    cd00143
    Location:23 → 291
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
    pfam07830
    Location:285 → 363
    PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

  6. XM_046919460.1 → XP_046775416.1  protein phosphatase 1A isoform X2

    UniProtKB/TrEMBL
    A0A8V0Z031, E1BVM8

  7. XM_046919459.1 → XP_046775415.1  protein phosphatase 1A isoform X1

    UniProtKB/TrEMBL
    A0A8V0YY86, A0A8V0Z031
Nucleotide Protein
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