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RASGEF1A RasGEF domain family member 1A [ Gallus gallus (chicken) ]

Gene ID: 423631, updated on 17-Aug-2024

Summary

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Symbol
RASGEF1Aprovided by CGNC
Full Name
RasGEF domain family member 1Aprovided by CGNC
Primary source
CGNC:1811
See related
Ensembl:ENSGALG00010011077
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See RASGEF1A in Genome Data Viewer
Location:
chromosome: 6
Exon count:
17
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 6 NC_052537.1 (5287482..5434128)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 6 NC_052578.1 (5173619..5320554)

Chromosome 6 - NC_052537.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101752332 Neighboring gene mannose binding lectin 2 Neighboring gene microRNA mir-12280 Neighboring gene chondroitin sulfate N-acetylgalactosaminyltransferase 2 Neighboring gene ret proto-oncogene Neighboring gene uncharacterized LOC121111190

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ras-GEF domain-containing family member 1A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052537.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    5287482..5434128
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004941966.4 → XP_004942023.1  ras-GEF domain-containing family member 1A isoform X1

    UniProtKB/TrEMBL
    A0A3Q3ADN1, A0A8V0YGI5
    Related
    ENSGALP00010015114.1, ENSGALT00010026535.1
    Conserved Domains (2) summary
    cd06224
    Location:57 → 174
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    pfam00617
    Location:228 → 421
    RasGEF; RasGEF domain

  2. XM_004941967.4 → XP_004942024.1  ras-GEF domain-containing family member 1A isoform X3

    UniProtKB/TrEMBL
    A0A8V0YGI5, E1BYX9
    Related
    ENSGALP00010015108.1, ENSGALT00010026527.1
    Conserved Domains (2) summary
    cd06224
    Location:49 → 166
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    pfam00617
    Location:220 → 413
    RasGEF; RasGEF domain

  3. XM_015288051.4 → XP_015143537.1  ras-GEF domain-containing family member 1A isoform X4

    UniProtKB/TrEMBL
    A0A8V0YGI5
    Conserved Domains (2) summary
    cd06224
    Location:41 → 158
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    pfam00617
    Location:212 → 405
    RasGEF; RasGEF domain

  4. XM_003641456.6 → XP_003641504.3  ras-GEF domain-containing family member 1A isoform X2

    UniProtKB/TrEMBL
    A0A3Q2U9B0, A0A8V0YGI5
    Related
    ENSGALP00010015105.1, ENSGALT00010026523.1
    Conserved Domains (2) summary
    cd06224
    Location:52 → 169
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    cd00155
    Location:219 → 462
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  5. XM_040702949.2 → XP_040558883.1  ras-GEF domain-containing family member 1A isoform X5

    UniProtKB/TrEMBL
    A0A8V0YGI5
    Conserved Domains (2) summary
    cd06224
    Location:3 → 101
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    smart00147
    Location:151 → 399
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052578.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    5173619..5320554
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040674983.2 → XP_040530917.1  ras-GEF domain-containing family member 1A isoform X1

    UniProtKB/TrEMBL
    A0A3Q3ADN1, A0A8V0YGI5
    Conserved Domains (2) summary
    cd06224
    Location:57 → 174
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    pfam00617
    Location:228 → 421
    RasGEF; RasGEF domain

  2. XM_040674985.2 → XP_040530919.1  ras-GEF domain-containing family member 1A isoform X3

    UniProtKB/TrEMBL
    A0A8V0YGI5, E1BYX9
    Conserved Domains (2) summary
    cd06224
    Location:49 → 166
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    pfam00617
    Location:220 → 413
    RasGEF; RasGEF domain

  3. XM_040674986.2 → XP_040530920.1  ras-GEF domain-containing family member 1A isoform X4

    UniProtKB/TrEMBL
    A0A8V0YGI5
    Conserved Domains (2) summary
    cd06224
    Location:41 → 158
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    pfam00617
    Location:212 → 405
    RasGEF; RasGEF domain

  4. XM_040674984.2 → XP_040530918.1  ras-GEF domain-containing family member 1A isoform X2

    UniProtKB/TrEMBL
    A0A3Q2U9B0, A0A8V0YGI5
    Conserved Domains (2) summary
    cd06224
    Location:52 → 169
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    cd00155
    Location:219 → 462
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  5. XM_040674987.2 → XP_040530921.1  ras-GEF domain-containing family member 1A isoform X5

    UniProtKB/TrEMBL
    A0A8V0YGI5
    Conserved Domains (2) summary
    cd06224
    Location:3 → 101
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    smart00147
    Location:151 → 399
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001031219.1: Suppressed sequence

    Description
    NM_001031219.1: This RefSeq was temporarily suppressed because there were several differences compared to available sequence data. These differences resulted in premature translation termination.
Nucleotide Protein Strain
Heading Accession and Version

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