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CG4462 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42376, updated on 4-Jan-2025

Summary

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Official Symbol
CG4462provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0038752
Locus tag
Dmel_CG4462
See related
AllianceGenome:FB:FBgn0038752
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG4462
Summary
Predicted to enable organic anion transmembrane transporter activity. Predicted to be involved in organic anion transport. Predicted to be located in plasma membrane. Is expressed in adult head and seminal receptacle. Orthologous to human SLC22A15 (solute carrier family 22 member 15). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG4462 in Genome Data Viewer
Location:
92B7-92B8; 3-67 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (19921744..19925371, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (15747466..15751093, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA::CR43282 Neighboring gene long non-coding RNA:CR46040 Neighboring gene hairpin RNA 1 Neighboring gene uncharacterized protein Neighboring gene Heparan sulfate 6-O-sulfotransferase Neighboring gene miranda

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Anion-sensitive fluorophore identifies the Drosophila swell-activated chloride channel in a genome-wide RNA interference screen. Stotz SC, et al. PLoS One, 2012. PMID 23056495, Free PMC Article
  2. Adaptive regulation of testis gene expression and control of male fertility by the Drosophila hairpin RNA pathway. [Corrected]. Wen J, et al. Mol Cell, 2015 Jan 8. PMID 25544562, Free PMC Article
  3. Transcriptional profiling of the sperm storage organs of Drosophila melanogaster. Prokupek AM, et al. Insect Mol Biol, 2009 Aug. PMID 19453766
  4. Genetic architecture of natural variation in visual senescence in Drosophila. Carbone MA, et al. Proc Natl Acad Sci U S A, 2016 Oct 25. PMID 27791033, Free PMC Article
  5. Crtc modulates fasting programs associated with 1-C metabolism and inhibition of insulin signaling. Wang T, et al. Proc Natl Acad Sci U S A, 2021 Mar 23. PMID 33723074, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables organic anion transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in organic anion transport ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG4462-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    19921744..19925371 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142592.2 → NP_650849.1  uncharacterized protein Dmel_CG4462 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650849.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VDS0
    Related
    FBpp0083259
    Conserved Domains (2) summary
    cd06174
    Location:149 → 284
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00898
    Location:126 → 532
    2A0119; cation transport protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SXB7 Q8SXB7
Q9VDS0 Q9VDS0

Gene LinkOut

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