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Hs6st - Heparan sulfate 6-O-sulfotransferase

Predicted to enable heparan sulfate 6-O-sulfotransferase activity. Involved in several processes, including heparan sulfate proteoglycan biosynthetic process; imaginal disc-derived wing margin morphogenesis; and regulation of imaginal disc growth. Predicted to be located in membrane. Is expressed in several structures, including dorsal ectoderm; dorsal epidermis primordium; dorsal pharyngeal muscle cell; embryonic/larval dorsal vessel; and tracheal primordium. Human ortholog(s) of this gene implicated in Paganini-Miozzo syndrome and hypogonadotropic hypogonadism 15 with or without anosmia. Orthologous to several human genes including HS6ST1 (heparan sulfate 6-O-sulfotransferase 1). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa