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eIF3g2 eukaryotic translation initiation factor 3 subunit g2 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42422, updated on 9-Dec-2024

Summary

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Official Symbol
eIF3g2provided by FlyBase
Official Full Name
eukaryotic translation initiation factor 3 subunit g2provided by FlyBase
Primary source
FLYBASE:FBgn0038796
Locus tag
Dmel_CG10881
See related
AllianceGenome:FB:FBgn0038796
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
cg10881; CG10881; Dmel\CG10881; eIF3-S4; eIF3gb
Summary
Predicted to enable mRNA binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex. Orthologous to human EIF3G (eukaryotic translation initiation factor 3 subunit G). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See eIF3g2 in Genome Data Viewer
Location:
92E8-92E8; 3-68 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (20408265..20409243)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (16233987..16234965)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Metallothionein C Neighboring gene Glial cell line-derived neurotrophic family receptor-like Neighboring gene Trimethyllysine hydroxylase Neighboring gene long non-coding RNA:CR44400 Neighboring gene long non-coding RNA:CR44401

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of Drosophila GDNF receptor-like and evidence for its evolutionarily conserved interaction with neural cell adhesion molecule (NCAM)/FasII. Kallijärvi J, et al. PLoS One, 2012. PMID 23284846, Free PMC Article
  2. A family knockout of all four Drosophila metallothioneins reveals a central role in copper homeostasis and detoxification. Egli D, et al. Mol Cell Biol, 2006 Mar. PMID 16508004, Free PMC Article
  3. Reduction in mutation frequency by very low-dose gamma irradiation of Drosophila melanogaster germ cells. Ogura K, et al. Radiat Res, 2009 Jan. PMID 19138046
  4. RACK1 controls IRES-mediated translation of viruses. Majzoub K, et al. Cell, 2014 Nov 20. PMID 25416947, Free PMC Article
  5. The gut-microbiota-brain axis in autism: what Drosophila models can offer? Salim S, et al. J Neurodev Disord, 2021 Sep 15. PMID 34525941, Free PMC Article

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables translation initiation factor activity IEA
Inferred from Electronic Annotation
more info
  
enables translation initiation factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in translational initiation ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of eukaryotic translation initiation factor 3 complex IEA
Inferred from Electronic Annotation
more info
  
part_of eukaryotic translation initiation factor 3 complex ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
eukaryotic translation initiation factor 3 subunit g2
Names
CG10881-PA
eIF3g paralogue b
eIF3g2-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    20408265..20409243
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142630.3 → NP_650887.1  eukaryotic translation initiation factor 3 subunit g2 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650887.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VDM6
    UniProtKB/TrEMBL
    F3YDD7
    Related
    FBpp0083293
    Conserved Domains (3) summary
    COG0724
    Location:171 → 256
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12408
    Location:194 → 270
    RRM_eIF3G_like; RNA recognition motif in eukaryotic translation initiation factor 3 subunit G (eIF-3G) and similar proteins
    pfam12353
    Location:28 → 137
    eIF3g; Eukaryotic translation initiation factor 3 subunit G
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VDM6.1 Q9VDM6

Gene LinkOut

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