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Stat92E - Signal-transducer and activator of transcription protein at 92E

Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and histone binding activity. Involved in several processes, including larval development; oogenesis; and regionalization. Located in cytoplasmic side of apical plasma membrane; cytosol; and nucleus. Is expressed in several structures, including follicle cell; germline cell; gut section; head epidermis primordium; and somatic cell of testis. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); breast cancer (multiple); carcinoma (multiple); reproductive organ cancer (multiple); and scleroderma (multiple). Orthologous to several human genes including STAT5A (signal transducer and activator of transcription 5A) and STAT5B (signal transducer and activator of transcription 5B). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa