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RNASEL ribonuclease L [ Gallus gallus (chicken) ]

Gene ID: 424410, updated on 3-Dec-2024

Summary

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Symbol
RNASELprovided by CGNC
Full Name
ribonuclease Lprovided by CGNC
Primary source
CGNC:2677
See related
Ensembl:ENSGALG00010009830
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See RNASEL in Genome Data Viewer
Location:
chromosome: 8
Exon count:
8
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 8 NC_052539.1 (5610224..5615728)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 8 NC_052580.1 (5622125..5627616)

Chromosome 8 - NC_052539.1Genomic Context describing neighboring genes Neighboring gene regulator of G-protein signaling 8 Neighboring gene regulator of G-protein signaling 16 Neighboring gene regulator of G protein signaling like 1 Neighboring gene glutamate-ammonia ligase Neighboring gene zinc finger protein 648

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA nuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
2-5A-dependent ribonuclease
Names
ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
NP_001026438.2
XP_040560473.1
XP_040560475.1
XP_040560476.1
XP_040560477.1
XP_046778468.1
XP_046778469.1
XP_046778470.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001031267.2 → NP_001026438.2  2-5A-dependent ribonuclease

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000237
    UniProtKB/TrEMBL
    A0A8V0XZ22, Q2PBC0
    Related
    ENSGALP00010013543.1, ENSGALT00010023471.1
    Conserved Domains (4) summary
    cd10423
    Location:576 → 687
    RNase_RNase-L; RNase domain (also known as the kinase extension nuclease domain) of RNase L
    PHA03095
    Location:37 → 296
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:55 → 86
    ANK; ANK repeat [structural motif]
    cl21453
    Location:375 → 507
    PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052539.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    5610224..5615728
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040704539.2 → XP_040560473.1  2-5A-dependent ribonuclease isoform X1

    UniProtKB/TrEMBL
    A0A8V0XZ22, Q2PBC0
    Conserved Domains (4) summary
    cd10423
    Location:576 → 687
    RNase_RNase-L; RNase domain (also known as the kinase extension nuclease domain) of RNase L
    PHA03095
    Location:37 → 296
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:55 → 86
    ANK; ANK repeat [structural motif]
    cl21453
    Location:375 → 507
    PKc_like; Protein Kinases, catalytic domain

  2. XM_040704543.2 → XP_040560477.1  2-5A-dependent ribonuclease isoform X1

    UniProtKB/TrEMBL
    A0A8V0XZ22, Q2PBC0
    Conserved Domains (4) summary
    cd10423
    Location:576 → 687
    RNase_RNase-L; RNase domain (also known as the kinase extension nuclease domain) of RNase L
    PHA03095
    Location:37 → 296
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:55 → 86
    ANK; ANK repeat [structural motif]
    cl21453
    Location:375 → 507
    PKc_like; Protein Kinases, catalytic domain

  3. XM_040704541.2 → XP_040560475.1  2-5A-dependent ribonuclease isoform X1

    UniProtKB/TrEMBL
    A0A8V0XZ22, Q2PBC0
    Conserved Domains (4) summary
    cd10423
    Location:576 → 687
    RNase_RNase-L; RNase domain (also known as the kinase extension nuclease domain) of RNase L
    PHA03095
    Location:37 → 296
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:55 → 86
    ANK; ANK repeat [structural motif]
    cl21453
    Location:375 → 507
    PKc_like; Protein Kinases, catalytic domain

  4. XM_040704542.2 → XP_040560476.1  2-5A-dependent ribonuclease isoform X1

    UniProtKB/TrEMBL
    A0A8V0XZ22, Q2PBC0
    Conserved Domains (4) summary
    cd10423
    Location:576 → 687
    RNase_RNase-L; RNase domain (also known as the kinase extension nuclease domain) of RNase L
    PHA03095
    Location:37 → 296
    PHA03095; ankyrin-like protein; Provisional
    sd00045
    Location:55 → 86
    ANK; ANK repeat [structural motif]
    cl21453
    Location:375 → 507
    PKc_like; Protein Kinases, catalytic domain

RNA

  1. XR_005861806.2 RNA Sequence

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052580.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    5622125..5627616
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046922512.1 → XP_046778468.1  2-5A-dependent ribonuclease isoform X1

    UniProtKB/TrEMBL
    Q2PBC0

  2. XM_046922513.1 → XP_046778469.1  2-5A-dependent ribonuclease isoform X1

    UniProtKB/TrEMBL
    Q2PBC0

  3. XM_046922514.1 → XP_046778470.1  2-5A-dependent ribonuclease isoform X1

    UniProtKB/TrEMBL
    Q2PBC0

RNA

  1. XR_006935391.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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