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LRRC8C leucine rich repeat containing 8 family member C [ Gallus gallus (chicken) ]

Gene ID: 424515, updated on 17-Aug-2024

Summary

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Symbol
LRRC8Cprovided by CGNC
Full Name
leucine rich repeat containing 8 family member Cprovided by CGNC
Primary source
CGNC:4629
See related
Ensembl:ENSGALG00010022831
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See LRRC8C in Genome Data Viewer
Location:
chromosome: 8
Exon count:
4
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 8 NC_052539.1 (14796600..14814126, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 8 NC_052580.1 (14803944..14821466, complement)

Chromosome 8 - NC_052539.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 326 Neighboring gene leucine rich repeat containing 8 family member D Neighboring gene uncharacterized LOC107056693 Neighboring gene kynurenine aminotransferase 3 Neighboring gene general transcription factor IIB

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
volume-regulated anion channel subunit LRRC8C

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052539.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    14796600..14814126 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015290662.4 → XP_015146148.1  volume-regulated anion channel subunit LRRC8C isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZQA9, A0A8V0ZQB4
    Related
    ENSGALP00010033656.1, ENSGALT00010055546.1
    Conserved Domains (4) summary
    cd00116
    Location:471 → 674
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:471 → 494
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12534
    Location:4 → 340
    Pannexin_like; Pannexin-like TM region of LRRC8
    pfam13855
    Location:639 → 697
    LRR_8; Leucine rich repeat

  2. XM_015290663.4 → XP_015146149.1  volume-regulated anion channel subunit LRRC8C isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZQB4, E1C957
    Related
    ENSGALP00010033665.1, ENSGALT00010055558.1
    Conserved Domains (3) summary
    COG4886
    Location:491 → 791
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:468 → 491
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12534
    Location:1 → 337
    Pannexin_like; Pannexin-like TM region of LRRC8

  3. XM_040704821.2 → XP_040560755.1  volume-regulated anion channel subunit LRRC8C isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZQB4, E1C957
    Conserved Domains (3) summary
    COG4886
    Location:491 → 791
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:468 → 491
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12534
    Location:1 → 337
    Pannexin_like; Pannexin-like TM region of LRRC8

  4. XM_040704820.2 → XP_040560754.1  volume-regulated anion channel subunit LRRC8C isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZQB4, E1C957
    Conserved Domains (3) summary
    COG4886
    Location:491 → 791
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:468 → 491
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12534
    Location:1 → 337
    Pannexin_like; Pannexin-like TM region of LRRC8

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052580.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    14803944..14821466 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040677355.2 → XP_040533289.1  volume-regulated anion channel subunit LRRC8C isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZQB4
    Conserved Domains (2) summary
    COG4886
    Location:494 → 794
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:471 → 494
    LRR_RI; leucine-rich repeat [structural motif]

  2. XM_040677356.2 → XP_040533290.1  volume-regulated anion channel subunit LRRC8C isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZQB4
    Conserved Domains (2) summary
    COG4886
    Location:491 → 791
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:468 → 491
    LRR_RI; leucine-rich repeat [structural motif]

  3. XM_040677358.2 → XP_040533292.1  volume-regulated anion channel subunit LRRC8C isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZQB4
    Conserved Domains (2) summary
    COG4886
    Location:491 → 791
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:468 → 491
    LRR_RI; leucine-rich repeat [structural motif]

  4. XM_040677357.2 → XP_040533291.1  volume-regulated anion channel subunit LRRC8C isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZQB4
    Conserved Domains (2) summary
    COG4886
    Location:491 → 791
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:468 → 491
    LRR_RI; leucine-rich repeat [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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